MAGEA2 Antikörper (N-Term)

Produktnummer ABIN390106

Produktdetails anti-MAGEA2 Antikörper

Target: MAGEA2 (Melanoma Antigen Family A, 2 (MAGEA2))

Bindungsspezifität: AA 81-108, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAGEA2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MAGEA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-108 amino acids from the N-terminal region of human MAGEA2.

Klon: RB2194

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:2000. FC: 1:25

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu MAGEA2

Target: MAGEA2 (Melanoma Antigen Family A, 2 (MAGEA2))

Andere Bezeichnung: MAGEA2 (MAGEA2 Produkte)

Synonyme: Mage-a2 antikoerper, MAGEA2 antikoerper, CT1.2 antikoerper, MAGE2 antikoerper, MAGEA2A antikoerper, melanoma antigen, family A, 2 antikoerper, melanoma-associated antigen 2 antikoerper, MAGE family member A2 antikoerper, Magea2 antikoerper, LOC706218 antikoerper, MAGEA2 antikoerper

Hintergrund: MAGEA2 is a member of the MAGEA gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 80 % sequence identity between each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are expressed at a high level in a number of tumors of various histologic types, and are silent in normal tissues with the exception of testis and placenta. The MAGEA genes are clustered on chromosome Xq28. They may be implicated in some hereditary disorders, such as dyskeratosis congenita. This gene has two identical copies at different loci.

Gen-ID: 4101

NCBI Accession: NP_005352, NP_705692, NP_786884, NP_786885

UniProt: P43356