Sclerostin Antikörper (AA 134-163)
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- Target Alle Sclerostin (SOST) Antikörper anzeigen
- Sclerostin (SOST)
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Bindungsspezifität
- AA 134-163
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Sclerostin Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Aufreinigung
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Immunogen
- This SOST antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 134-163 amino acids from the Central region of human SOST.
- Klon
- RB13011
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product SOST Primärantikörper
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- Applikationshinweise
- WB: 1:1000. IHC-P: 1:10~50
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Haltbarkeit
- 6 months
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- Target
- Sclerostin (SOST)
- Andere Bezeichnung
- SOST (SOST Produkte)
- Synonyme
- LOC100313724 antikoerper, CDD antikoerper, VBCH antikoerper, 5430411E23Rik antikoerper, sclerostin antikoerper, LOC100313724 antikoerper, SOST antikoerper, Sost antikoerper
- Hintergrund
- Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of the sclerostin gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease.
- Molekulargewicht
- 24031
- Gen-ID
- 50964
- NCBI Accession
- NP_079513
- UniProt
- Q9BQB4
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