GRB2 Antikörper (AA 187-216)
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- Target Alle GRB2 Antikörper anzeigen
- GRB2 (Growth Factor Receptor-Bound Protein 2 (GRB2))
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Bindungsspezifität
- AA 187-216
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser GRB2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Homologie
- X, C, M, Rat
- Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This GRB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-216 amino acids from human GRB2.
- Klon
- RB11305-11306
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product GRB2 Primärantikörper
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- Applikationshinweise
- WB: 1:1000. IHC-P: 1:10~50
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Haltbarkeit
- 6 months
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Targeting the C-terminal focal adhesion kinase scaffold in pancreatic cancer." in: Cancer letters, Vol. 353, Issue 2, pp. 281-9, (2014) (PubMed).
: "
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Targeting the C-terminal focal adhesion kinase scaffold in pancreatic cancer." in: Cancer letters, Vol. 353, Issue 2, pp. 281-9, (2014) (PubMed).
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- Target
- GRB2 (Growth Factor Receptor-Bound Protein 2 (GRB2))
- Andere Bezeichnung
- GRB2 (GRB2 Produkte)
- Hintergrund
- GRB2 binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway.
- Molekulargewicht
- 25206
- Gen-ID
- 2885
- NCBI Accession
- NP_002077, NP_987102
- UniProt
- P62993
- Pathways
- RTK Signalweg, T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Actin Filament Polymerization, Hepatitis C, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, EGFR Downregulation
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