Kallikrein 5 Antikörper (AA 144-174)

Produktnummer ABIN390305

Produktdetails anti-Kallikrein 5 Antikörper

Target: Kallikrein 5 (KLK5)

Bindungsspezifität: AA 144-174

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Kallikrein 5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This Kallikrein 5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 144-174 amino acids from the Central region of human Kallikrein 5.

Klon: RB6112

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-Kallikrein 5 Antikörper (ABIN390305)

Jennemann, Rabionet, Gorgas, Epstein, Dalpke, Rothermel, Bayerle, van der Hoeven, Imgrund, Kirsch, Nickel, Willecke, Riezman, Gröne, Sandhoff: "Loss of ceramide synthase 3 causes lethal skin barrier disruption." in: Human molecular genetics, Vol. 21, Issue 3, pp. 586-608, (2012) (PubMed).

Details zu Kallikrein 5

Target: Kallikrein 5 (KLK5)

Abstract: KLK5 Produkte

Hintergrund: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. KLK5 expression is up-regulated by estrogens and progestins. The protein is secreted and may be involved in desquamation in the epidermis.

Molekulargewicht: 32020

Gen-ID: 25818

NCBI Accession: NP_001070959, NP_001070960, NP_036559

UniProt: Q9Y337

Pathways: Komplementsystem, Regulation of G-Protein Coupled Receptor Protein Signaling