Kallikrein 5 Antikörper (AA 144-174)
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- Target Alle Kallikrein 5 (KLK5) Antikörper anzeigen
- Kallikrein 5 (KLK5)
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Bindungsspezifität
- AA 144-174
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Kallikrein 5 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Aufreinigung
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Immunogen
- This Kallikrein 5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 144-174 amino acids from the Central region of human Kallikrein 5.
- Klon
- RB6112
- Isotyp
- Ig Fraction
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- Applikationshinweise
- WB: 1:1000. WB: 1:1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Haltbarkeit
- 6 months
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Loss of ceramide synthase 3 causes lethal skin barrier disruption." in: Human molecular genetics, Vol. 21, Issue 3, pp. 586-608, (2012) (PubMed).
: "
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Loss of ceramide synthase 3 causes lethal skin barrier disruption." in: Human molecular genetics, Vol. 21, Issue 3, pp. 586-608, (2012) (PubMed).
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- Target
- Kallikrein 5 (KLK5)
- Abstract
- KLK5 Produkte
- Hintergrund
- Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. KLK5 expression is up-regulated by estrogens and progestins. The protein is secreted and may be involved in desquamation in the epidermis.
- Molekulargewicht
- 32020
- Gen-ID
- 25818
- NCBI Accession
- NP_001070959, NP_001070960, NP_036559
- UniProt
- Q9Y337
- Pathways
- Komplementsystem, Regulation of G-Protein Coupled Receptor Protein Signaling
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