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Parkin Antikörper (C-Term)
PARK2
Reaktivität: Human, Maus
WB, IF, FACS, IHC (p)
Wirt: Kaninchen
Polyclonal
RB07373
unconjugated
Produktnummer ABIN2840772
Produktdetails anti-Parkin Antikörper
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Target
Alle Parkin (PARK2) Antikörper anzeigen
Parkin (PARK2)
(Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2))
Bindungsspezifität
Alle Epitope für Parkin Antikörper
AA 387-417, C-Term
Reaktivität
Alle Reaktivitäten für Parkin Antikörper
Human, Maus
Wirt
Alle Wirte für Parkin Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für Parkin Antikörper
Polyklonal
Konjugat
Alle Konjugate für Parkin Antikörper
Dieser Parkin Antikörper ist unkonjugiert
Applikation
Alle Applikationen für Parkin Antikörper
Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Aufreinigung
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This Parkin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 387-417 amino acids from the C-terminal region of human Parkin.
Klon
RB07373
Isotyp
Ig Fraction
Alternativen
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Anwendungsinformationen
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Applikationshinweise
IF: 1:10~50. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. IHC-P: 1:50~100. FC: 1:10~50
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Haltbarkeit
6 months
Details zu Parkin
(ausblenden)
Target
Parkin (PARK2)
(Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2))
Andere Bezeichnung
Parkin (PARK2 Produkte )
Synonyme
CG10523 antikoerper, Dmel\\CG10523 antikoerper, Dpark antikoerper, SD01679 antikoerper, dpk antikoerper, AR-JP antikoerper, LPRS2 antikoerper, PDJ antikoerper, PRKN antikoerper, Park antikoerper, Prkn antikoerper, si:ch211-123f21.1 antikoerper, zgc:112390 antikoerper, pdr-1 antikoerper, PARK2 antikoerper, parkin antikoerper, parkin RBR E3 ubiquitin protein ligase antikoerper, Parkinson disease (autosomal recessive, juvenile) 2, parkin antikoerper, park antikoerper, PRKN antikoerper, Prkn antikoerper, prkn antikoerper, CpipJ_CPIJ014867 antikoerper, Park2 antikoerper
Hintergrund
Parkinson is the second most common neurodegenerative disease after Alzheimers. About 1 percent of people over the age of 65 and 3 percent of people over the age of 75 are affected by the disease. The mutation is the most common cause of Parkinson disease identified to date. The function of Park2 is not well-known, however, it may play a role in the ubiquitin-mediated proteolytic pathway. Mutations in this gene are known to cause autosomal recessive juvenile parkinsonism. Alternative splicing of this gene produces three known products of undetermined function.
Molekulargewicht
51641
Gen-ID
5071
NCBI Accession
NP_004553 , NP_054642 , NP_054643
UniProt
O60260
Pathways
Autophagie , Ubiquitin Proteasome Pathway
Zuletzt angesehen
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