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Glucagon Antikörper (N-Term)

GCG Reaktivität: Human, Maus WB, IHC (p), FACS Wirt: Kaninchen Polyclonal RB19443 unconjugated
Produktnummer ABIN390411
  • Target Alle Glucagon (GCG) Antikörper anzeigen
    Glucagon (GCG)
    Bindungsspezifität
    • 16
    • 16
    • 11
    • 8
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 25-54, N-Term
    Reaktivität
    • 134
    • 53
    • 48
    • 16
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 89
    • 34
    • 14
    • 4
    • 1
    Kaninchen
    Klonalität
    • 96
    • 45
    Polyklonal
    Konjugat
    • 80
    • 11
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Glucagon Antikörper ist unkonjugiert
    Applikation
    • 53
    • 52
    • 29
    • 17
    • 15
    • 13
    • 13
    • 11
    • 10
    • 10
    • 9
    • 8
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This GCG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-54 amino acids from the N-terminal region of human GCG.
    Klon
    RB19443
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product GCG Primärantikörper
  • Applikationshinweise
    WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Target
    Glucagon (GCG)
    Andere Bezeichnung
    GCG (GCG Produkte)
    Synonyme
    GLP1 antikoerper, GLP2 antikoerper, GRPP antikoerper, GLP-1 antikoerper, Glu antikoerper, PPG antikoerper, GCG antikoerper, gcg-A antikoerper, gcg1 antikoerper, glucagon antikoerper, glucagon L homeolog antikoerper, GCG antikoerper, Gcg antikoerper, gcg.L antikoerper
    Hintergrund
    GCG is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon.
    Molekulargewicht
    20909
    Gen-ID
    2641
    NCBI Accession
    NP_002045
    UniProt
    P01275
    Pathways
    Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, cAMP Metabolic Process, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Negative Regulation of intrinsic apoptotic Signaling
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