Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Aufreinigung
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This P450R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 462-488 amino acids from the Central region of human P450R.
CPR antikoerper, CYPOR antikoerper, P450R antikoerper, POR antikoerper, CCR antikoerper, CG11567 antikoerper, DMR antikoerper, DmCPR antikoerper, Dmel\\CG11567 antikoerper, NCPR antikoerper, P450 antikoerper, cpr antikoerper, zgc:110032 antikoerper, npr antikoerper, xpor antikoerper, 4933424M13Rik antikoerper, PORCINO antikoerper, T5J17.90 antikoerper, T5J17_90 antikoerper, TFC C antikoerper, TUBULIN-FOLDING COFACTOR C antikoerper, cytochrome p450 oxidoreductase antikoerper, P450 (cytochrome) oxidoreductase antikoerper, ADP-ribosylation factor interacting protein 2 antikoerper, Cytochrome P450 reductase antikoerper, P450 (cytochrome) oxidoreductase a antikoerper, P450 (cytochrome) oxidoreductase L homeolog antikoerper, NADPH--cytochrome P450 reductase antikoerper, C-CAP/cofactor C-like domain-containing protein antikoerper, POR antikoerper, Arfip2 antikoerper, Por antikoerper, Cpr antikoerper, pora antikoerper, por.L antikoerper, LOC100406157 antikoerper, por antikoerper, LOC100619047 antikoerper
Hintergrund
P450R is an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in its gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome.