SETD8 Antikörper (AA 220-249)

Produktnummer ABIN390472

Produktdetails anti-SETD8 Antikörper

Target: SETD8 (SET Domain Containing (Lysine Methyltransferase) 8 (SETD8))

Bindungsspezifität: AA 220-249

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SETD8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Homologie: B

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This SETD8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 220-249 amino acids from the Central region of human SETD8.

Klon: RB18964

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu SETD8

Target: SETD8 (SET Domain Containing (Lysine Methyltransferase) 8 (SETD8))

Andere Bezeichnung: SETD8 (SETD8 Produkte)

Synonyme: KMT5A antikoerper, PR-Set7 antikoerper, SET07 antikoerper, SET8 antikoerper, 2410195B05Rik antikoerper, AA617402 antikoerper, AW536475 antikoerper, PR-SET7 antikoerper, setd8b antikoerper, wu:fc23f12 antikoerper, zgc:171649 antikoerper, Pr-set7 antikoerper, RGD1305893 antikoerper, Setd8 antikoerper, kmt5a antikoerper, kmt5a-a antikoerper, setd8 antikoerper, setd8-a antikoerper, set8a antikoerper, setd8a antikoerper, wu:fj33f02 antikoerper, zgc:153719 antikoerper, lysine methyltransferase 5A antikoerper, lysine methyltransferase 5Ab antikoerper, lysine methyltransferase 5A S homeolog antikoerper, lysine methyltransferase 5Aa antikoerper, KMT5A antikoerper, Kmt5a antikoerper, kmt5ab antikoerper, kmt5a.S antikoerper, kmt5aa antikoerper

Hintergrund: SETD8 is a histone methyltransferase that specifically monomethylates 'Lys-20' of histone H4. H4 'Lys-20' monomethylation is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression. The protein mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes. It is required for cell proliferation, probably by contributing to the maintenance of proper higher order structure of DNA during mitosis. It is also involved in chromosome condensation and proper cytokinesis. Nucleosomes are preferred as substrate compared to free histones.

Molekulargewicht: 42890

Gen-ID: 387893

NCBI Accession: NP_065115

UniProt: Q9NQR1