This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This CTSE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 157-187 amino acids from the Central region of human CTSE.
CATE antikoerper, A430072O03Rik antikoerper, C920004C08Rik antikoerper, CE antikoerper, CatE antikoerper, CEA antikoerper, CEB antikoerper, Ctsea antikoerper, CTSE antikoerper, ce1 antikoerper, ce2 antikoerper, cate antikoerper, CE1 antikoerper, ce1-A antikoerper, ctse antikoerper, CE2 antikoerper, ce2-A antikoerper, cathepsin E antikoerper, cathepsin E L homeolog antikoerper, cathepsin E S homeolog antikoerper, CTSE antikoerper, Ctse antikoerper, TP03_0056 antikoerper, Smp_184930 antikoerper, ctse antikoerper, ctse.L antikoerper, ctse.S antikoerper
Hintergrund
CTSE is a gastric aspartyl protease that functions as a disulfide-linked homodimer. This protease, which is a member of the peptidase C1 family, has a specificity similar to that of pepsin A and cathepsin D. It is an intracellular proteinase that does not appear to be involved in the digestion of dietary protein and is found in highest concentration in the surface of epithelial mucus-producing cells of the stomach. It is the first aspartic proteinase expressed in the fetal stomach and is found in more than half of gastric cancers. It appears, therefore, to be an oncofetal antigen.