GZMB Antikörper (C-Term)
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- Target Alle GZMB Antikörper anzeigen
- GZMB (Granzyme B (GZMB))
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Bindungsspezifität
- AA 175-203, C-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser GZMB Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Aufreinigung
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Immunogen
- This GZMB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 175-203 amino acids from the C-terminal region of human GZMB.
- Klon
- RB19353
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product GZMB Primärantikörper
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- Applikationshinweise
- WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Haltbarkeit
- 6 months
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- Target
- GZMB (Granzyme B (GZMB))
- Andere Bezeichnung
- GZMB (GZMB Produkte)
- Synonyme
- CCPI antikoerper, CGL-1 antikoerper, CGL1 antikoerper, CSP-B antikoerper, CSPB antikoerper, CTLA1 antikoerper, CTSGL1 antikoerper, HLP antikoerper, SECT antikoerper, granzyme B antikoerper, GZMB antikoerper
- Hintergrund
- Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response.
- Molekulargewicht
- 27716
- Gen-ID
- 3002
- NCBI Accession
- NP_004122
- UniProt
- P10144
- Pathways
- Apoptose, Caspase Kaskade in der Apoptose
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