This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This COL6A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 831-858 amino acids from the C-terminal region of human COL6A1.
CBR antikoerper, SDR21C1 antikoerper, hCBR1 antikoerper, OPLL antikoerper, AI747156 antikoerper, Col6a-1 antikoerper, RGD1565398 antikoerper, COL6A1 antikoerper, carbonyl reductase 1 antikoerper, collagen type VI alpha 1 chain antikoerper, collagen, type VI, alpha 1 antikoerper, collagen, type VI, alpha 1 L homeolog antikoerper, collagen type VI alpha 3 chain antikoerper, collagen alpha-1(VI) chain antikoerper, CBR1 antikoerper, COL6A1 antikoerper, Col6a1 antikoerper, col6a1.L antikoerper, COL6A3 antikoerper, col6a1 antikoerper, LOC100623720 antikoerper
Hintergrund
The collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagens are extracellular matrix proteins and have a triple-helical domain as their common structural element. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha1(VI), alpha2(VI), and alpha3(VI) chains. The protein COL6A1 is the alpha 1 subunit of type VI collagen (alpha1(VI) chain). Mutations in the genes that code for the collagen VI subunits result in the autosomal dominant disorder, Bethlem myopathy.