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MTBP Antikörper (C-Term)

Name: MTBP Antikörper (C-Term)
SKU: ABIN390601
Price: 467.5 EUR
Availability: InStock

MTBP Reaktivität: Human WB, IHC (p), FACS Wirt: Kaninchen Polyclonal RB20020 unconjugated

Western blot analysis of MTBP antibody (C-term) (ABIN390601 and ABIN2840917) in K562 cell line lysates (35 μg/lane). (MTBP Antikörper (C-Term))

Flow cytometric analysis of K562 cells using MTBP Antibody (C-term)(bottom histogram) compared to a negative control cell (top histogram)FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. (MTBP Antikörper (C-Term))

FACS

Formalin-fixed and paraffin-embedded human prostate carcinoma reacted with MTBP Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (MTBP Antikörper (C-Term))

IHC (p)

3 Abbildungen

Produktnummer ABIN390601

Datenblatt (PDF)

Target Alle MTBP Antikörper anzeigen

MTBP (MDM2 Binding Protein (MTBP))
Bindungsspezifität
15

5

4

3

2

2

1

1

1

1

1
AA 853-881, C-Term
Reaktivität
42

18

2

2

2

2

2

2

1

1

1

1

1
Human
Wirt
40

2
Kaninchen
Passende Sekundärantikörper
Klonalität
40

2
Polyklonal
Konjugat
18

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser MTBP Antikörper ist unkonjugiert
Applikation
31

13

13

13

6

4

3

3

2

2

2
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Homologie

M

Aufreinigung

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen

This MTBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 853-881 amino acids from the C-terminal region of human MTBP.

Klon

RB20020

Isotyp

Ig Fraction
anti-MDM2 Binding Protein (MTBP) antibody
MTBP Reaktivität: Human WB, IHC, FACS Wirt: Kaninchen Polyclonal unconjugated

anti-MDM2 Binding Protein (MTBP) (AA 567-724) antibody
MTBP Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated

anti-MDM2 Binding Protein (MTBP) (AA 667-812) antibody
MTBP Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal PHL-1 unconjugated

anti-MDM2 Binding Protein (MTBP) (AA 23-350) antibody
MTBP Reaktivität: Human WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

anti-MDM2 Binding Protein (MTBP) (Middle Region 2) antibody
MTBP Reaktivität: Human WB, ELISA, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-MDM2 Binding Protein (MTBP) (AA 122-139) antibody
MTBP Reaktivität: Human WB, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated

anti-MDM2 Binding Protein (MTBP) (AA 122-139), (Middle Region) antibody
MTBP Reaktivität: Human WB, EIA, IF Wirt: Kaninchen Polyclonal unconjugated

anti-MDM2 Binding Protein (MTBP) (AA 567-724) antibody (HRP)
MTBP Reaktivität: Human ELISA Wirt: Kaninchen Polyclonal HRP

anti-MDM2 Binding Protein (MTBP) (AA 567-724) antibody (FITC)
MTBP Reaktivität: Human Wirt: Kaninchen Polyclonal FITC

anti-MDM2 Binding Protein (MTBP) (AA 567-724) antibody (Biotin)
MTBP Reaktivität: Human ELISA Wirt: Kaninchen Polyclonal Biotin

Applikationshinweise

WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit

6 months
Target

MTBP (MDM2 Binding Protein (MTBP))

Andere Bezeichnung

MTBP (MTBP Produkte)

Hintergrund

MTBP inhibits cell migration in vitro and suppresses the invasive behavior of tumor cells. The protein may play a role in MDM2-dependent TP53/p53 homeostasis in unstressed cells. The protein inhibits autoubiquitination of MDM2, thereby enhancing MDM2 stability. This promotes MDM2-mediated ubiquitination of TP53/p53 and its subsequent degradation.

Molekulargewicht

102193

Gen-ID

27085

NCBI Accession

NP_071328

UniProt

Q96DY7