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XPO1 Antikörper (C-Term)

Name: XPO1 Antikörper (C-Term)
SKU: ABIN390636
Price: 445.5 EUR
Availability: InStock

XPO1 Reaktivität: Human IHC (p), FACS Wirt: Kaninchen Polyclonal RB19972 unconjugated

Formalin-fixed and paraffin-embedded human brain tissue reacted with XPO1 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (XPO1 Antikörper (C-Term))

IHC (p)

Flow cytometric analysis of widr cells using XPO1 Antibody (C-term)(bottom histogram) compared to a negative control cell (top histogram). (XPO1 Antikörper (C-Term))

FACS

2 Abbildungen

(1 reference)

Produktnummer ABIN390636

Datenblatt (PDF)

Target Alle XPO1 Antikörper anzeigen

XPO1 (Exportin 1 (XPO1))
Bindungsspezifität
15

10

6

5

4

2

2

2

2

2

1

1

1

1

1
AA 817-846, C-Term
Reaktivität
72

37

36

8

8

5

4

4

4

4

3

3

2

1

1

1

1

1
Human
Wirt
66

6
Kaninchen
Passende Sekundärantikörper
Klonalität
57

15
Polyklonal
Konjugat
39

4

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
Dieser XPO1 Antikörper ist unkonjugiert
Applikation
46

15

15

14

14

14

7

7

5

5

4

2

1

1

1
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Homologie

M, Rat

Aufreinigung

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen

This XPO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 817-846 amino acids from the C-terminal region of human XPO1.

Klon

RB19972

Isotyp

Ig Fraction

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XPO1 Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

anti-Exportin 1 (XPO1) (C-Term) antibody
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XPO1 Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated

anti-Exportin 1 (XPO1) (AA 917-1071) antibody
XPO1 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

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XPO1 Reaktivität: Human, Maus, Ratte WB, ELISA Wirt: Kaninchen Polyclonal unconjugated

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XPO1 Reaktivität: Human, Ratte WB, ELISA, IHC (p), IF (cc), IF (p), ICC, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

anti-Exportin 1 (XPO1) antibody
XPO1 Reaktivität: Human ELISA, IHC Wirt: Kaninchen Monoclonal 9F2 unconjugated Recombinant Antibody

anti-Exportin 1 (XPO1) (AA 2-122) antibody
XPO1 Reaktivität: Human, Maus, Ratte, Hund, Huhn WB, IF Wirt: Maus Monoclonal 17-Exportin unconjugated

Applikationshinweise

IHC-P: 1:50~100. FC: 1:10~50

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit

6 months
Sharma, Åkerström, Sharma, Chow, Teow, Abrenica, Booth, Booth, Mirazimi, Lal: "SARS-CoV 9b protein diffuses into nucleus, undergoes active Crm1 mediated nucleocytoplasmic export and triggers apoptosis when retained in the nucleus." in: PLoS ONE, Vol. 6, Issue 5, pp. e19436, (2011) (PubMed).
Target

XPO1 (Exportin 1 (XPO1))

Andere Bezeichnung

XPO1 (XPO1 Produkte)

Synonyme

CG13387 antikoerper, CRM1 antikoerper, Crm1 antikoerper, DCRM1 antikoerper, Dmel\\CG13387 antikoerper, Emb antikoerper, XPO-1 antikoerper, XPO1 antikoerper, Xpo1 antikoerper, crm1 antikoerper, dCRM1 antikoerper, l(2)k16715 antikoerper, 18.m06600 antikoerper, DDBDRAFT_0183812 antikoerper, DDBDRAFT_0234066 antikoerper, DDB_0183812 antikoerper, DDB_0234066 antikoerper, exportin-1 antikoerper, LOC100220104 antikoerper, emb antikoerper, exp1 antikoerper, Xpo antikoerper, AA420417 antikoerper, Exp1 antikoerper, embargoed antikoerper, exportin 1 antikoerper, putative exportin 1 antikoerper, chromosome region maintenance protein 1 antikoerper, exportin-1 antikoerper, exportin 1 (CRM1 homolog, yeast) antikoerper, exportin 1 S homeolog antikoerper, emb antikoerper, cgd3_3060 antikoerper, Tc00.1047053511725.150 antikoerper, Tb11.01.5940 antikoerper, BBOV_II007220 antikoerper, LMJF_32_1100 antikoerper, xpo1 antikoerper, Xpo1 antikoerper, XPO1 antikoerper, LOC100165622 antikoerper, LOC100633509 antikoerper, xpo1.S antikoerper

Hintergrund

XPO1 mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1.

Molekulargewicht

123386

Gen-ID

7514

NCBI Accession

NP_003391

UniProt

O14980

Pathways

M Phase