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XPO1 Antikörper (C-Term)

XPO1 Reaktivität: Human IHC (p), FACS Wirt: Kaninchen Polyclonal RB19972 unconjugated
Produktnummer ABIN390636
  • Target Alle XPO1 Antikörper anzeigen
    XPO1 (Exportin 1 (XPO1))
    Bindungsspezifität
    • 15
    • 10
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 817-846, C-Term
    Reaktivität
    • 74
    • 37
    • 36
    • 8
    • 8
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 68
    • 6
    Kaninchen
    Klonalität
    • 57
    • 17
    Polyklonal
    Konjugat
    • 41
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser XPO1 Antikörper ist unkonjugiert
    Applikation
    • 47
    • 16
    • 16
    • 15
    • 14
    • 14
    • 7
    • 7
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    Homologie
    M, Rat
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This XPO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 817-846 amino acids from the C-terminal region of human XPO1.
    Klon
    RB19972
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product XPO1 Primärantikörper
  • Applikationshinweise
    IHC-P: 1:50~100. FC: 1:10~50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Sharma, Åkerström, Sharma, Chow, Teow, Abrenica, Booth, Booth, Mirazimi, Lal: "SARS-CoV 9b protein diffuses into nucleus, undergoes active Crm1 mediated nucleocytoplasmic export and triggers apoptosis when retained in the nucleus." in: PLoS ONE, Vol. 6, Issue 5, pp. e19436, (2011) (PubMed).

  • Target
    XPO1 (Exportin 1 (XPO1))
    Andere Bezeichnung
    XPO1 (XPO1 Produkte)
    Hintergrund
    XPO1 mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1.
    Molekulargewicht
    123386
    Gen-ID
    7514
    NCBI Accession
    NP_003391
    UniProt
    O14980
    Pathways
    M Phase
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