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Glucagon Antikörper (C-Term)

Name: Glucagon Antikörper (C-Term)
SKU: ABIN390769
Price: 445.5 EUR
Availability: InStock

GCG Reaktivität: Human WB, IF, IHC (p), FACS Wirt: Kaninchen Polyclonal RB19525 unconjugated

Immunohistochemical analysis of paraffin-embedded Human pancreas section using Pink1 C. (Glucagon Antikörper (C-Term))

IHC

Western blot analysis of Glucagon Antibody (C-term) (ABIN390769 and ABIN2841027) in Jurkat cell line lysates (35 μg/lane). (Glucagon Antikörper (C-Term))

Confocal immunofluorescent analysis of Glucagon Antibody (C-term) (ABIN390769 and ABIN2841027) with pancreas tissue followed by Alexa Fluor? (Glucagon Antikörper (C-Term))

All lanes : Anti-Glucagon Antibody (C-term) at 1:1000 dilution Lane 1: NC-1 whole cell lysate Lane 2: Humanbrain lysate Lane 3: Jurkat whole cell lysate Lysates/proteins at 20 μg per lane. (Glucagon Antikörper (C-Term))

Overlay histogram showing Jurkat cells stained with (ABIN390769 and ABIN2841027)(green line). (Glucagon Antikörper (C-Term))

FACS

Immunohistochemical analysis of paraffin-embedded human liver tissue using (ABIN390769 and ABIN2841027) performed on the Leica® BOND RXm. (Glucagon Antikörper (C-Term))

IHC (p)

6 Abbildungen

Produktnummer ABIN390769

Datenblatt (PDF)

Target Alle Glucagon (GCG) Antikörper anzeigen

Glucagon (GCG)
Bindungsspezifität
17

16

10

7

6

6

5

4

3

3

3

2

2

2

1

1

1

1

1

1

1

1

1

1
AA 119-148, C-Term
Reaktivität
134

53

49

16

7

6

4

3

3

3

3

2

2

1

1

1
Human
Wirt
89

34

14

4

1
Kaninchen
Passende Sekundärantikörper
Klonalität
96

45
Polyklonal
Konjugat
80

11

6

5

4

3

3

3

3

3

3

3

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser Glucagon Antikörper ist unkonjugiert
Applikation
53

52

29

16

15

13

13

11

10

10

9

8

4

3

2

2

2

2

2

1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Aufreinigung

This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen

This Glucagon antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 119-148 amino acids from the C-terminal region of human Glucagon.

Klon

RB19525

Isotyp

Ig Fraction

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Applikationshinweise

IF: 1:10~50. WB: 1:1000. WB: 1:1000. IHC-P-Leica: 1:1000. FC: 1:25. IHC: 1:125

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit

6 months
Target

Glucagon (GCG)

Andere Bezeichnung

Glucagon (GCG Produkte)

Synonyme

GLP1 antikoerper, GLP2 antikoerper, GRPP antikoerper, GLP-1 antikoerper, Glu antikoerper, PPG antikoerper, GCG antikoerper, gcg-A antikoerper, gcg1 antikoerper, glucagon antikoerper, glucagon L homeolog antikoerper, GCG antikoerper, Gcg antikoerper, gcg.L antikoerper

Hintergrund

Glucagon is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon.

Molekulargewicht

20909

Gen-ID

2641

NCBI Accession

NP_002045

UniProt

P01275

Pathways

Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, cAMP Metabolic Process, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Negative Regulation of intrinsic apoptotic Signaling