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VCP Antikörper (C-Term)

Name: VCP Antikörper (C-Term)
SKU: ABIN390907
Price: 467.5 EUR
Availability: InStock

VCP Reaktivität: Human WB, IHC (p), FACS Wirt: Kaninchen Polyclonal RB21276 unconjugated

Western blot analysis of VCP Antibody (C-term) (ABIN390907 and ABIN2841113) in Jurkat, 293, MDA-M cell line lysates (35 μg/lane). (VCP Antikörper (C-Term))

Flow cytometric analysis of MDA-231 cells using VCP Antibody (C-term)(bottom histogram) compared to a negative control cell (top histogram). (VCP Antikörper (C-Term))

FACS

Formalin-fixed and paraffin-embedded human brain tissue reacted with VCP Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (VCP Antikörper (C-Term))

IHC (p)

3 Abbildungen

(1 reference)

Produktnummer ABIN390907

Datenblatt (PDF)

Target Alle VCP Antikörper anzeigen

VCP (Valosin Containing Protein (VCP))
Bindungsspezifität
11

10

9

7

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 726-755, C-Term
Reaktivität
89

48

40

14

5

5

5

5

4

3

3

2

2

2

1

1

1
Human
Wirt
74

18

2
Kaninchen
Passende Sekundärantikörper
Klonalität
66

28
Polyklonal
Konjugat
58

7

6

3

3

3

3

3

3

3

1

1
Dieser VCP Antikörper ist unkonjugiert
Applikation
61

36

24

20

18

12

12

11

8

2

2

2

2

1

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Homologie

B, Zf, M, Pig, Rat, X

Aufreinigung

This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen

This VCP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 726-755 amino acids from the C-terminal region of human VCP.

Klon

RB21276

Isotyp

Ig Fraction

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VCP Reaktivität: Human, Ratte WB, IHC (p), ICC, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

anti-Valosin Containing Protein (VCP) (AA 732-760) antibody
VCP Reaktivität: Human, Maus, Ratte WB, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit

6 months
Ayaki, Ito, Fukushima, Inoue, Kondo, Ikemoto, Asano, Shodai, Fujita, Fukui, Morino, Nakano, Kusaka, Yamashita, Ihara, Matsumoto, Kawamata, Urushitani, Kawakami, Takahashi: "Immunoreactivity of valosin-containing protein in sporadic amyotrophic lateral sclerosis and in a case of its novel mutant." in: Acta neuropathologica communications, Vol. 2, pp. 172, (2015) (PubMed).
Target

VCP (Valosin Containing Protein (VCP))

Andere Bezeichnung

VCP (VCP Produkte)

Hintergrund

VCP is a member of a family that includes putative ATP-binding proteins involved in vesicle transport and fusion, 26S proteasome function, and assembly of peroxisomes. This protein, as a structural protein, is associated with clathrin, and heat-shock protein Hsc70, to form a complex. It has been implicated in a number of cellular events that are regulated during mitosis, including homotypic membrane fusion, spindle pole body function, and ubiquitin-dependent protein degradation.

Molekulargewicht

89322

Gen-ID

7415

NCBI Accession

NP_009057

UniProt

P55072

Pathways

ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Ubiquitin Proteasome Pathway