This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This HEXA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 142-170 amino acids from the N-terminal region of human HEXA.
HEXA is the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases.