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PKC zeta Antikörper (N-Term)

PRKCZ Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB01027 unconjugated
Produktnummer ABIN391018
  • Target Alle PKC zeta (PRKCZ) Antikörper anzeigen
    PKC zeta (PRKCZ) (Protein Kinase C, zeta (PRKCZ))
    Bindungsspezifität
    • 35
    • 27
    • 13
    • 10
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 166-197, N-Term
    Reaktivität
    • 111
    • 63
    • 41
    • 9
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 122
    • 3
    • 1
    Kaninchen
    Klonalität
    • 113
    • 13
    Polyklonal
    Konjugat
    • 57
    • 9
    • 8
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser PKC zeta Antikörper ist unkonjugiert
    Applikation
    • 95
    • 54
    • 33
    • 26
    • 26
    • 20
    • 19
    • 9
    • 7
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This PKC zeta antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 166-197 amino acids from the N-terminal region of human PKC zeta.
    Klon
    RB01027
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product PRKCZ Primärantikörper
  • Applikationshinweise
    WB: 1:1000. IHC-P: 1:10~50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Lerner-Marmarosh, Miralem, Gibbs, Maines: "Regulation of TNF-alpha-activated PKC-zeta signaling by the human biliverdin reductase: identification of activating and inhibitory domains of the reductase." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 21, Issue 14, pp. 3949-62, (2007) (PubMed).

  • Target
    PKC zeta (PRKCZ) (Protein Kinase C, zeta (PRKCZ))
    Andere Bezeichnung
    PKC zeta (PRKCZ Produkte)
    Synonyme
    TPKC antikoerper, PKCzeta antikoerper, prkcz-A antikoerper, pkc-zeta antikoerper, PRKCZ antikoerper, pkc2 antikoerper, PKC-ZETA antikoerper, PKC2 antikoerper, AI098070 antikoerper, C80388 antikoerper, Pkcz antikoerper, R74924 antikoerper, aPKCzeta antikoerper, zetaPKC antikoerper, 14-3-3-zetaisoform antikoerper, r14-3-3 antikoerper, pkcz antikoerper, si:ch211-150o23.4 antikoerper, protein kinase C zeta L homeolog antikoerper, protein kinase C zeta antikoerper, protein kinase C, zeta antikoerper, prkcz.L antikoerper, PRKCZ antikoerper, prkcz antikoerper, Prkcz antikoerper
    Hintergrund
    Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a constitutive kinase activity which is independent of calcium, and PKC activators, phosphatidylserine and diacylglycerol. Furthermore, it is insensitive to PKC inhibitors and cannot be activated by phorbol ester. The structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC.
    Molekulargewicht
    67660
    Gen-ID
    5590
    NCBI Accession
    NP_001028753, NP_001028754, NP_001229803, NP_002735
    UniProt
    Q05513
    Pathways
    NF-kappaB Signalweg, RTK Signalweg, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Membrane, Production of Molecular Mediator of Immune Response, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
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