MOBKL1A Antikörper (C-Term)
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- Target Alle MOBKL1A (MOB1B) Antikörper anzeigen
- MOBKL1A (MOB1B) (MOB Kinase Activator 1B (MOB1B))
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Bindungsspezifität
- AA 177-206, C-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser MOBKL1A Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Homologie
- M, Rat
- Aufreinigung
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Immunogen
- This MOB4A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 177-206 amino acids from the C-terminal region of human MOB4A.
- Klon
- RB12538
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product MOB1B Primärantikörper
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- Applikationshinweise
- IF: 1:10~50. WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Haltbarkeit
- 6 months
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Cancer susceptibility and embryonic lethality in Mob1a/1b double-mutant mice. ..." in: The Journal of clinical investigation, Vol. 122, Issue 12, pp. 4505-18, (2012) (PubMed).
: "Mutual dependence of Mob1 and the chromosomal passenger complex for localization during mitosis." in: Molecular biology of the cell, Vol. 21, Issue 3, pp. 380-92, (2010) (PubMed).
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Cancer susceptibility and embryonic lethality in Mob1a/1b double-mutant mice. ..." in: The Journal of clinical investigation, Vol. 122, Issue 12, pp. 4505-18, (2012) (PubMed).
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- Target
- MOBKL1A (MOB1B) (MOB Kinase Activator 1B (MOB1B))
- Andere Bezeichnung
- MOB4A (MOB1B Produkte)
- Hintergrund
- MOB4A is similar to the yeast Mob1 protein. Yeast Mob1 binds Mps1p, a protein kinase essential for spindle pole body duplication and mitotic checkpoint regulation. Mob4A regulates NDR1 and NDR2 kinase activity, widely expressed nuclear serine-threonine kinases that have been implicated in cell proliferation and/or tumor progression.
- Molekulargewicht
- 25091
- Gen-ID
- 92597
- NCBI Accession
- NP_001231695, NP_775739
- UniProt
- Q7L9L4
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