MOBKL1A Antikörper (C-Term)

Produktnummer ABIN391030

Produktdetails anti-MOBKL1A Antikörper

Target: MOBKL1A (MOB1B) (MOB Kinase Activator 1B (MOB1B))

Bindungsspezifität: AA 177-206, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MOBKL1A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: M, Rat

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This MOB4A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 177-206 amino acids from the C-terminal region of human MOB4A.

Klon: RB12538

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: IF: 1:10~50. WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-MOBKL1A Antikörper (ABIN391030)

Nishio, Hamada, Kawahara, Sasaki, Noguchi, Chiba, Mizuno, Suzuki, Dong, Tokuda, Morikawa, Hikasa, Eggenschwiler, Yabuta, Nojima, Nakagawa, Hata, Nishina, Mimori, Mori, Sasaki, Mak, Nakano, Itami et al.: "Cancer susceptibility and embryonic lethality in Mob1a/1b double-mutant mice. ..." in: The Journal of clinical investigation, Vol. 122, Issue 12, pp. 4505-18, (2012) (PubMed).

Wilmeth, Shrestha, Montaño, Rashe, Shuster: "Mutual dependence of Mob1 and the chromosomal passenger complex for localization during mitosis." in: Molecular biology of the cell, Vol. 21, Issue 3, pp. 380-92, (2010) (PubMed).

Details zu MOBKL1A

Target: MOBKL1A (MOB1B) (MOB Kinase Activator 1B (MOB1B))

Andere Bezeichnung: MOB4A (MOB1B Produkte)

Hintergrund: MOB4A is similar to the yeast Mob1 protein. Yeast Mob1 binds Mps1p, a protein kinase essential for spindle pole body duplication and mitotic checkpoint regulation. Mob4A regulates NDR1 and NDR2 kinase activity, widely expressed nuclear serine-threonine kinases that have been implicated in cell proliferation and/or tumor progression.

Molekulargewicht: 25091

Gen-ID: 92597

NCBI Accession: NP_001231695, NP_775739

UniProt: Q7L9L4