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PKM2 Antikörper (C-Term)

Name: PKM2 Antikörper (C-Term)
SKU: ABIN391053
Price: 445.5 EUR
Availability: InStock

PKM2 Reaktivität: Human, Maus, Ratte, Affe WB, IHC (p), IF Wirt: Kaninchen Polyclonal RB3697 unconjugated

All lanes : Anti-PKM2 Antibody at 1:1000 dilution Lane 1: Hela whole cell lysate Lane 2: MCF-7 whole cell lysate Lysates/proteins at 20 μg per lane. (PKM2 Antikörper (C-Term))

Pyruvate Kinase (PKM2) Antibody (C-term) (ABIN391053 and ABIN2837941) immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. (PKM2 Antikörper (C-Term))

IHC (p)

Western blot analysis of hPKM2- in cell line(lane 1) and mouse brain tissue(lane 2) lysates (35 μg/lane). (PKM2 Antikörper (C-Term))

Fluorescent confocal image of MCF7 cells stained with Pyruvate Kinase (PKM2) (C-term) antibody. (PKM2 Antikörper (C-Term))

All lanes : Anti-hPKM2- at 1:2000 dilution Lane 1: Hela whole cell lysate Lane 2: A549 whole cell lysate Lane 3: NIH/3T3 whole cell lysate Lane 4: C2C12 whole cell lysate Lane 5: PC-12 whole cell lysate Lysates/proteins at 20 μg per lane. (PKM2 Antikörper (C-Term))

5 Abbildungen

(1 reference)

Produktnummer ABIN391053

Datenblatt (PDF)

Target Alle PKM2 Antikörper anzeigen

PKM2 (Pyruvate Kinase M2 (PKM2))
Bindungsspezifität
21

16

16

11

7

7

7

7

7

6

6

6

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 476-505, C-Term
Reaktivität
149

104

92

4

3

2

2

2

2

2

1

1

1
Human, Maus, Ratte, Affe
Wirt
127

22

5
Kaninchen
Passende Sekundärantikörper
Klonalität
133

21
Polyklonal
Konjugat
57

12

9

9

9

9

9

9

3

3

2

2

2

2

2

2

2

2

2

2

2

2

1
Dieser PKM2 Antikörper ist unkonjugiert
Applikation
85

34

27

27

23

19

14

11

9

7

7

5

2

2

2

1

1

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Aufreinigung

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen

This Pyruvate Kinase (PKM2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 476-505 amino acids from the C-terminal region of human Pyruvate Kinase (PKM2).

Klon

RB3697

Isotyp

Ig Fraction

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PKM2 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Pyruvate Kinase M2 (PKM2) (pTyr105) antibody
PKM2 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

anti-Pyruvate Kinase M2 (PKM2) (AA 383-417), (C-Term) antibody
PKM2 Reaktivität: Human WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB18405 unconjugated

anti-Pyruvate Kinase M2 (PKM2) (AA 476-505) antibody
PKM2 Reaktivität: Human, Maus, Ratte, Primate WB, IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated

anti-Pyruvate Kinase M2 (PKM2) (AA 116-145) antibody
PKM2 Reaktivität: Human WB, IHC, ELISA, FACS Wirt: Kaninchen Polyclonal unconjugated

anti-Pyruvate Kinase M2 (PKM2) (AA 255-350) antibody
PKM2 Reaktivität: Human, Maus, Ratte WB, ELISA, FACS, IHC (p), IF (cc), IF (p), ICC, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

anti-Pyruvate Kinase M2 (PKM2) (AA 121-151), (N-Term) antibody
PKM2 Reaktivität: Human, Maus WB Wirt: Kaninchen Polyclonal RB5870 unconjugated

anti-Pyruvate Kinase M2 (PKM2) (AA 116-145), (N-Term) antibody
PKM2 Reaktivität: Human WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB15338 unconjugated

anti-Pyruvate Kinase M2 (PKM2) (AA 1-531) antibody
PKM2 Reaktivität: Human WB, PLA Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

IF: 1:200. WB: 1:1000. WB: 1:1000. WB: 1:2000. IHC-P: 1:50~1:100

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung

Avoid freeze-thaw cycles.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.

Haltbarkeit

6 months
Kienzl, Sarg, Golderer, Obrist, Werner, Werner-Felmayer, Lindner, Maglione, Schneeberger, Margreiter, Brandacher: "Proteomic profiling of acute cardiac allograft rejection." in: Transplantation, Vol. 88, Issue 4, pp. 553-60, (2009) (PubMed).
Target

PKM2 (Pyruvate Kinase M2 (PKM2))

Andere Bezeichnung

PKM2 (PKM2 Produkte)

Synonyme

CTHBP antikoerper, OIP3 antikoerper, PK3 antikoerper, PKM2 antikoerper, TCB antikoerper, THBP1 antikoerper, AA414905 antikoerper, AL024370 antikoerper, AL024424 antikoerper, Pk-2 antikoerper, Pk-3 antikoerper, Pk3 antikoerper, Pkm2 antikoerper, PKM12 antikoerper, PKM antikoerper, pyruvate kinase M1/2 antikoerper, pyruvate kinase, muscle antikoerper, PKM antikoerper, Pkm antikoerper

Hintergrund

There are 4 isozymes of pyruvate kinase in mammals: L, R, M1 and M2. PKM2 is a pyruvate kinase that catalyzes the production of phosphoenolpyruvate from pyruvate and ATP. This protein has been shown to interact with thyroid hormone, and thus may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis.

Molekulargewicht

57937

Gen-ID

5315

NCBI Accession

NP_001193725, NP_001193726, NP_001193727, NP_001193728, NP_002645, NP_872270, NP_872271

UniProt

P14618

Pathways

Warburg Effekt