DTYMK Antikörper (C-Term)

Produktnummer ABIN391075

Produktdetails anti-DTYMK Antikörper

Target: DTYMK (Deoxythymidylate Kinase (Thymidylate Kinase) (DTYMK))

Bindungsspezifität: AA 164-194, C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DTYMK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This DTYMK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 164-194 amino acids from the C-terminal region of human DTYMK.

Klon: RB5576

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu DTYMK

Target: DTYMK (Deoxythymidylate Kinase (Thymidylate Kinase) (DTYMK))

Andere Bezeichnung: DTYMK (DTYMK Produkte)

Synonyme: tymk antikoerper, wu:fa12c02 antikoerper, wu:fb14h07 antikoerper, wu:ft84f02 antikoerper, zgc:123174 antikoerper, DTYMK antikoerper, MGC81047 antikoerper, Tb08.28L1.680 antikoerper, Tb08.10J17.310 antikoerper, DDBDRAFT_0188698 antikoerper, DDBDRAFT_0230101 antikoerper, DDB_0188698 antikoerper, DDB_0230101 antikoerper, AU044245 antikoerper, CDC8 antikoerper, D10Ertd203e antikoerper, TMPK antikoerper, TYPK antikoerper, Tmk antikoerper, mtmk antikoerper, PP3731 antikoerper, TYMK antikoerper, deoxythymidylate kinase antikoerper, deoxythymidylate kinase (thymidylate kinase) antikoerper, deoxythymidylate kinase S homeolog antikoerper, thymidylate kinase antikoerper, dTMP kinase antikoerper, Dtymk antikoerper, dtymk antikoerper, DTYMK antikoerper, dtymk.S antikoerper, Tmk antikoerper, CNC04630 antikoerper, Tb927.8.3510 antikoerper, Tb927.8.3910 antikoerper, Ndas_4954 antikoerper, Mesil_2461 antikoerper, Slip_0046 antikoerper, Trad_0568 antikoerper, Olsu_1446 antikoerper, Acear_0042 antikoerper, Igag_1070 antikoerper, LOC100195817 antikoerper

Hintergrund: Thymidylate kinase (DTYMK) catalyzes the phosphorylation of dTMP to form dTDP in the dTTP synthesis pathway for DNA synthesis. DTYMK is essential for DNA synthesis and is an important intermediate enzyme in the pathway of many pyrimidine analog drugs, including 5-Fluorouracil (5-FU), the chemotherapeutic drug of choice for several solid tumors. The human DTYMK gene was isolated via functional complementation of a Saccharomyces cerevisiae cell cycle mutant, cdc8. DTYMK mRNA levels and enzyme activities are regulated at the level of cell cycle and cell growth pathways.

Molekulargewicht: 23819

Gen-ID: 1841

NCBI Accession: NP_036277

UniProt: P23919

Pathways: Nucleotide Phosphorylation