CKM Antikörper (C-Term)

Produktnummer ABIN391096

Produktdetails anti-CKM Antikörper

Target: CKM (Creatine Kinase, Muscle (CKM))

Bindungsspezifität: AA 283-313, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CKM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Homologie: B, Pig, Rb

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This CKM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 283-313 amino acids from the C-terminal region of human CKM.

Klon: RB5382

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-CKM Antikörper (ABIN391096)

Yang, Fann, Chang, Tai, Jiang, Kao: "Regulation of sodium-calcium exchanger activity by creatine kinase under energy-compromised conditions." in: The Journal of biological chemistry, Vol. 285, Issue 36, pp. 28275-85, (2010) (PubMed).

Details zu CKM

Target: CKM (Creatine Kinase, Muscle (CKM))

Andere Bezeichnung: CKM (CKM Produkte)

Synonyme: CKMM antikoerper, M-CK antikoerper, Ckmm antikoerper, MCK antikoerper, ckmm antikoerper, m-ck antikoerper, CKM antikoerper, CK-M antikoerper, cb51 antikoerper, ckm antikoerper, mck antikoerper, wu:fa28d05 antikoerper, ckm3 antikoerper, wu:fb55e09 antikoerper, zgc:64204 antikoerper, zgc:92070 antikoerper, creatine kinase, M-type antikoerper, creatine kinase, muscle antikoerper, creatine kinase, M-type L homeolog antikoerper, creatine kinase, muscle a antikoerper, creatine kinase, muscle b antikoerper, CKM antikoerper, Ckm antikoerper, ckm.L antikoerper, ckm antikoerper, ckma antikoerper, ckmb antikoerper

Hintergrund: Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa. The CKM isoform, predominant in skeletal muscle and heart tissue, is a cytoplasmic enzyme involved in energy homeostasis and is an important serum marker for myocardial infarction. CKM reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in striated muscle as well as in other tissues, and as a heterodimer with a similar brain isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family.

Molekulargewicht: 43101

Gen-ID: 1158

NCBI Accession: NP_001815

UniProt: P06732