PDXK Antikörper (N-Term)

Produktnummer ABIN391110

Produktdetails anti-PDXK Antikörper

Target: PDXK (Pyridoxal Kinase (PDXK))

Bindungsspezifität: AA 1-30, N-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDXK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This PDXK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human PDXK.

Klon: RB5460

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu PDXK

Target: PDXK (Pyridoxal Kinase (PDXK))

Andere Bezeichnung: PDXK (PDXK Produkte)

Synonyme: C21orf124 antikoerper, C21orf97 antikoerper, PKH antikoerper, PNK antikoerper, 2310036D04Rik antikoerper, AA119688 antikoerper, C77999 antikoerper, Pdxk antikoerper, PSPTO5521 antikoerper, DDBDRAFT_0190079 antikoerper, DDBDRAFT_0191114 antikoerper, DDB_0190079 antikoerper, DDB_0191114 antikoerper, ATSOS4 antikoerper, K18L3.1 antikoerper, K18L3_1 antikoerper, SALT OVERLY SENSITIVE 4 antikoerper, pdxk antikoerper, si:dkey-263m10.2 antikoerper, si:dz69g10.1 antikoerper, cb1056 antikoerper, pdxkl antikoerper, si:dkey-281i8.2 antikoerper, wu:fa55a03 antikoerper, wu:fb10c12 antikoerper, zgc:101900 antikoerper, pyridoxal kinase antikoerper, pyridoxal (pyridoxine, vitamin B6) kinase antikoerper, Pyridoxal kinase antikoerper, pfkB-like carbohydrate kinase family protein antikoerper, pyridoxal (pyridoxine, vitamin B6) kinase b antikoerper, pyridoxal (pyridoxine, vitamin B6) kinase a antikoerper, PDXK antikoerper, Pdxk antikoerper, pdxY antikoerper, pdxK antikoerper, Bphyt_1541 antikoerper, pykA antikoerper, Kfla_4736 antikoerper, Kvar_1290 antikoerper, Mrub_2507 antikoerper, BC1002_1103 antikoerper, Fbal_1661 antikoerper, Lbys_0710 antikoerper, Intca_0131 antikoerper, Deima_3190 antikoerper, Mesop_1158 antikoerper, LOC100283562 antikoerper, pdxk antikoerper, SOS4 antikoerper, pdxkb antikoerper, pdxka antikoerper

Hintergrund: Pyridoxal kinase (PDXK) converts vitamin B6 to pyridoxal-5-phosphate (PLP), an essential cofactor in the intermediate metabolism of amino acids and neurotransmitters. The PDXK gene encodes a 312-amino acid polypeptide, and expression of the cDNA reveals pyridoxal kinase activity. Northern blot analysis revealed that a major 1.5-kb PDXK transcript is expressed in all tissues tested. The expression of PDXK shows circadian oscillations. The expression of Pdxk in mouse liver and brain is regulated by the 3 PAR bZIP transcription factors, Dbp, Hlf, and Tef, which also show circadian oscillations in expression. Mice devoid of all 3 transcription factors show decreased levels of brain PLP, serotonin, and dopamine, and are highly susceptible to frequently lethal generalized spontaneous and audiogenic epilepsies.

Molekulargewicht: 35102

Gen-ID: 8566

NCBI Accession: NP_003672

UniProt: O00764