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PNCK Antikörper (C-Term)

PNCK Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB1253-1254 unconjugated
Produktnummer ABIN391139
  • Target Alle PNCK Antikörper anzeigen
    PNCK (Pregnancy Up-Regulated Non-Ubiquitously Expressed CaM Kinase (PNCK))
    Bindungsspezifität
    • 15
    • 14
    • 7
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 314-343, C-Term
    Reaktivität
    • 53
    • 13
    • 13
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Human
    Wirt
    • 51
    • 2
    Kaninchen
    Klonalität
    • 53
    Polyklonal
    Konjugat
    • 14
    • 6
    • 5
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PNCK Antikörper ist unkonjugiert
    Applikation
    • 27
    • 22
    • 13
    • 13
    • 9
    • 4
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This PNCK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 314-343 amino acids from the C-terminal region of human PNCK.
    Klon
    RB1253-1254
    Isotyp
    Ig Fraction
  • Applikationshinweise
    WB: 1:1000. IHC-P: 1:10~50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Deb, Zuo, Wang, Barndt, Cheema, Sengupta, Coticchia, Johnson: "Pnck induces ligand-independent EGFR degradation by probable perturbation of the Hsp90 chaperone complex." in: American journal of physiology. Cell physiology, Vol. 300, Issue 5, pp. C1139-54, (2011) (PubMed).

    Deb, Coticchia, Barndt, Zuo, Dickson, Johnson: "Pregnancy-upregulated nonubiquitous calmodulin kinase induces ligand-independent EGFR degradation." in: American journal of physiology. Cell physiology, Vol. 295, Issue 2, pp. C365-77, (2008) (PubMed).

  • Target
    PNCK (Pregnancy Up-Regulated Non-Ubiquitously Expressed CaM Kinase (PNCK))
    Andere Bezeichnung
    PNCK (PNCK Produkte)
    Synonyme
    BSTK3 antikoerper, CaMK1b antikoerper, Bstk3 antikoerper, CaMKIbeta2 antikoerper, CaMKlb2 antikoerper, Camk1b antikoerper, Punc antikoerper, caMKlb1 antikoerper, pregnancy up-regulated nonubiquitous CaM kinase antikoerper, pregnancy upregulated non-ubiquitously expressed CaM kinase antikoerper, PNCK antikoerper, Pnck antikoerper
    Hintergrund
    Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.
    Molekulargewicht
    38500
    Gen-ID
    139728
    NCBI Accession
    NP_001034671, NP_001129212
    UniProt
    Q6P2M8
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