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STRADB Antikörper (C-Term)

STRADB Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB15723 unconjugated
Produktnummer ABIN391172
  • Target Alle STRADB Antikörper anzeigen
    STRADB (STE20-Related Kinase Adaptor beta (STRADB))
    Bindungsspezifität
    • 14
    • 8
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 274-303, C-Term
    Reaktivität
    • 28
    • 27
    • 3
    • 1
    • 1
    • 1
    Human
    Wirt
    • 41
    • 2
    • 1
    Kaninchen
    Klonalität
    • 42
    • 1
    Polyklonal
    Konjugat
    • 23
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser STRADB Antikörper ist unkonjugiert
    Applikation
    • 33
    • 23
    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This ALS2CR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 274-303 amino acids from the C-terminal region of human ALS2CR2.
    Klon
    RB15723
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product STRADB Primärantikörper
  • Applikationshinweise
    WB: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Target
    STRADB (STE20-Related Kinase Adaptor beta (STRADB))
    Andere Bezeichnung
    ALS2CR2 (STRADB Produkte)
    Synonyme
    Als2cr2 antikoerper, RGD1559449 antikoerper, als2cr2 antikoerper, MGC82468 antikoerper, STRADB antikoerper, ALS2CR2 antikoerper, AA792893 antikoerper, B830008M19 antikoerper, D1Ucla2 antikoerper, ILPIP antikoerper, ILPIPA antikoerper, PRO1038 antikoerper, Papk antikoerper, Syradb antikoerper, CALS-21 antikoerper, PAPK antikoerper, STE20-related kinase adaptor beta antikoerper, STE20-related kinase adaptor beta L homeolog antikoerper, Stradb antikoerper, STRADB antikoerper, stradb.L antikoerper
    Hintergrund
    ALS2CR2 potentiates the antiapoptotic activity of XIAP by enhancing XIAP-mediated activation of JNK1 (MAPK8) and other JNK family members, but not by modulating XIAP-mediated caspase inhibition. Expression of a catalytically inactive TAK1 (MAP3K7) mutant blocks the XIAP/ALS2CR2 activation of JNK1. In vivo coprecipitation experiments show that both ALS2CR2 and XIAP interact with TAK1 and TRAF6. It has been proposed that XIAP-mediated protection from apoptosis utilizes both a JNK1 activation pathway that involves ALS2CR2 and a caspase inhibition pathway that is independent of ALS2CR2.
    Molekulargewicht
    47026
    Gen-ID
    55437
    NCBI Accession
    NP_001193793, NP_061041
    UniProt
    Q9C0K7
    Pathways
    AMPK Signaling
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