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PANK2 Antikörper (AA 180-210)

PANK2 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB5487 unconjugated
Produktnummer ABIN391238
  • Target Alle PANK2 Antikörper anzeigen
    PANK2 (Pantothenate Kinase 2 (PANK2))
    Bindungsspezifität
    • 15
    • 7
    • 6
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 180-210
    Reaktivität
    • 40
    • 21
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    Human
    Wirt
    • 49
    • 5
    Kaninchen
    Klonalität
    • 50
    • 5
    Polyklonal
    Konjugat
    • 21
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PANK2 Antikörper ist unkonjugiert
    Applikation
    • 43
    • 25
    • 13
    • 13
    • 7
    • 7
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This PANK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 180-210 amino acids from the Central region of human PANK2.
    Klon
    RB5487
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product PANK2 Primärantikörper
  • Applikationshinweise
    WB: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Target
    PANK2 (Pantothenate Kinase 2 (PANK2))
    Andere Bezeichnung
    PANK2 (PANK2 Produkte)
    Synonyme
    ATPANK2 antikoerper, F10M6.180 antikoerper, F10M6_180 antikoerper, pantothenate kinase 2 antikoerper, PANK2 antikoerper, C20orf48 antikoerper, HARP antikoerper, HSS antikoerper, NBIA1 antikoerper, PKAN antikoerper, 4933409I19Rik antikoerper, AI642621 antikoerper, pantothenate kinase 2 antikoerper, pantothenate kinase 2, mitochondrial antikoerper, ribonuclease A family member 11 (inactive) antikoerper, PANK2 antikoerper, Tsp_01576 antikoerper, LOC100539295 antikoerper, Pank2 antikoerper, RNASE11 antikoerper
    Hintergrund
    Pantothenate kinase is an essential regulatory enzyme in CoA biosynthesis, catalyzing the cytosolic phosphorylation of pantothenate (vitamin B5), N-pantothenoylcysteine, and pantetheine. CoA is the major acyl carrier, playing a central role in intermediary and fatty acid metabolism. In both yeast and fly, each with only 1 pantothenate kinase gene, the null mutant is inviable. Mutations in PANK2 are the cause of pantothenate kinase-associated neurodegeneration (PKAN), formerly known as Hallervorden-Spatz syndrome (HSS). PKAN is an autosomal recessive neurodegenerative disorder associated with iron accumulation in the brain. Mutations in PANK2 are the cause of hypoprebetalipoproteinemia, acanthocytosis, retinitis pigmentosa, and pallidal degeneration (HARP).
    Molekulargewicht
    62681
    Gen-ID
    80025
    NCBI Accession
    NP_079236, NP_705902, NP_705904
    UniProt
    Q9BZ23
    Pathways
    Ribonucleoside Biosynthetic Process
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