PANK2 Antikörper (AA 180-210)
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- Target Alle PANK2 Antikörper anzeigen
- PANK2 (Pantothenate Kinase 2 (PANK2))
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Bindungsspezifität
- AA 180-210
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PANK2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Aufreinigung
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Immunogen
- This PANK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 180-210 amino acids from the Central region of human PANK2.
- Klon
- RB5487
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product PANK2 Primärantikörper
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- Applikationshinweise
- WB: 1:1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Haltbarkeit
- 6 months
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- Target
- PANK2 (Pantothenate Kinase 2 (PANK2))
- Andere Bezeichnung
- PANK2 (PANK2 Produkte)
- Synonyme
- ATPANK2 antikoerper, F10M6.180 antikoerper, F10M6_180 antikoerper, pantothenate kinase 2 antikoerper, PANK2 antikoerper, C20orf48 antikoerper, HARP antikoerper, HSS antikoerper, NBIA1 antikoerper, PKAN antikoerper, 4933409I19Rik antikoerper, AI642621 antikoerper, pantothenate kinase 2 antikoerper, pantothenate kinase 2, mitochondrial antikoerper, ribonuclease A family member 11 (inactive) antikoerper, PANK2 antikoerper, Tsp_01576 antikoerper, LOC100539295 antikoerper, Pank2 antikoerper, RNASE11 antikoerper
- Hintergrund
- Pantothenate kinase is an essential regulatory enzyme in CoA biosynthesis, catalyzing the cytosolic phosphorylation of pantothenate (vitamin B5), N-pantothenoylcysteine, and pantetheine. CoA is the major acyl carrier, playing a central role in intermediary and fatty acid metabolism. In both yeast and fly, each with only 1 pantothenate kinase gene, the null mutant is inviable. Mutations in PANK2 are the cause of pantothenate kinase-associated neurodegeneration (PKAN), formerly known as Hallervorden-Spatz syndrome (HSS). PKAN is an autosomal recessive neurodegenerative disorder associated with iron accumulation in the brain. Mutations in PANK2 are the cause of hypoprebetalipoproteinemia, acanthocytosis, retinitis pigmentosa, and pallidal degeneration (HARP).
- Molekulargewicht
- 62681
- Gen-ID
- 80025
- NCBI Accession
- NP_079236, NP_705902, NP_705904
- UniProt
- Q9BZ23
- Pathways
- Ribonucleoside Biosynthetic Process
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