PDXK Antikörper (C-Term)
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- Target Alle PDXK Antikörper anzeigen
- PDXK (Pyridoxal Kinase (PDXK))
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Bindungsspezifität
- AA 242-272, C-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PDXK Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Aufreinigung
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Immunogen
- This PDXK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 242-272 amino acids from the C-terminal region of human PDXK.
- Klon
- RB5462
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product PDXK Primärantikörper
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anti-Pyridoxal Kinase (PDXK) (AA 29-253) antibody
PDXK Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Pyridoxal Kinase (PDXK) (AA 29-285) antibodyPDXK Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Pyridoxal Kinase (PDXK) (AA 35-251) antibodyPDXK Reaktivität: Ratte WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Pyridoxal Kinase (PDXK) antibodyPDXK Reaktivität: Human WB, IHC, IF, IHC (p), FACS Wirt: Maus Monoclonal 5H5 unconjugated
anti-Pyridoxal Kinase (PDXK) (AA 1-312) antibodyPDXK Reaktivität: Human WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Pyridoxal Kinase (PDXK) (AA 51-160) antibodyPDXK Reaktivität: Human WB, ELISA Wirt: Maus Polyclonal unconjugated
anti-Pyridoxal Kinase (PDXK) (AA 1-312) antibodyPDXK Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 4G6 unconjugated
anti-Pyridoxal Kinase (PDXK) (AA 1-30), (N-Term) antibodyPDXK Reaktivität: Human, Maus WB Wirt: Kaninchen Polyclonal RB5460 unconjugated
anti-Pyridoxal Kinase (PDXK) (AA 1-312) antibodyPDXK Reaktivität: Human WB, IHC (p) Wirt: Maus Monoclonal 1007CT2-1-1 unconjugated
anti-Pyridoxal Kinase (PDXK) antibodyPDXK Reaktivität: Human, Maus, Ratte WB, IF Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB: 1:1000. IHC-P: 1:50~100
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Haltbarkeit
- 6 months
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- Target
- PDXK (Pyridoxal Kinase (PDXK))
- Andere Bezeichnung
- PDXK (PDXK Produkte)
- Hintergrund
- Pyridoxal kinase (PDXK) converts vitamin B6 to pyridoxal-5-phosphate (PLP), an essential cofactor in the intermediate metabolism of amino acids and neurotransmitters. The PDXK gene encodes a 312-amino acid polypeptide, and expression of the cDNA reveals pyridoxal kinase activity. Northern blot analysis revealed that a major 1.5-kb PDXK transcript is expressed in all tissues tested. The expression of PDXK shows circadian oscillations. The expression of Pdxk in mouse liver and brain is regulated by the 3 PAR bZIP transcription factors, Dbp, Hlf, and Tef, which also show circadian oscillations in expression. Mice devoid of all 3 transcription factors show decreased levels of brain PLP, serotonin, and dopamine, and are highly susceptible to frequently lethal generalized spontaneous and audiogenic epilepsies.
- Molekulargewicht
- 35102
- Gen-ID
- 8566
- NCBI Accession
- NP_003672
- UniProt
- O00764
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