CAMKII gamma Antikörper (C-Term)

Produktnummer ABIN391313

Produktdetails anti-CAMKII gamma Antikörper

Target: CAMKII gamma (CAMK2G) (Calcium/calmodulin-Dependent Protein Kinase II gamma (CAMK2G))

Bindungsspezifität: AA 309-338, C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CAMKII gamma Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This CAMK2G (CAMK2 gamma) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 309-338 amino acids from the C-terminal region of human CAMK2G (CAMK2 gamma).

Klon: RB1246

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:500-1000. WB: 1:500. WB: 1:2000. IHC-P: 1:50~100. WB: 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-CAMKII gamma Antikörper (ABIN391313)

Jiang, Wu, Lu, Zhang, Yu, Gan, Wu, Xu, Zheng, Zhang, Xu, Ma, Gan, Huang, Yu, Huang, Xu: "Activation of CaMKIIγ potentiates T-cell acute lymphoblastic leukemia leukemogenesis via phosphorylating FOXO3a." in: Oncotarget, Vol. 8, Issue 43, pp. 75050-75064, (2017) (PubMed).

Details zu CAMKII gamma

Target: CAMKII gamma (CAMK2G) (Calcium/calmodulin-Dependent Protein Kinase II gamma (CAMK2G))

Andere Bezeichnung: CAMK2G (CAMK2 gamma) (CAMK2G Produkte)

Synonyme: CAMK antikoerper, CAMK-II antikoerper, CAMKG antikoerper, 5930429P18Rik antikoerper, Camkg antikoerper, calcium/calmodulin dependent protein kinase II gamma antikoerper, calcium/calmodulin-dependent protein kinase II gamma antikoerper, CAMK2G antikoerper, Camk2g antikoerper

Hintergrund: CaM-kinase II (CAMK2) is a prominent Ser/Thr protein kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Likely autophosphorylation of Thr-286 allows the kinase to switch from a calmodulin-dependent to a calmodulin-independent state. CAMK2 is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits.

Molekulargewicht: 62607

Gen-ID: 818

NCBI Accession: NP_001213, NP_751909, NP_751913

UniProt: Q13555

Pathways: WNT Signalweg, Interferon-gamma Pathway, Hormone Transport, Myometrial Relaxation and Contraction, Regulation of long-term Neuronal Synaptic Plasticity