MAP3K12 Antikörper (C-Term)

Produktnummer ABIN391319

Produktdetails anti-MAP3K12 Antikörper

Target: MAP3K12 (Mitogen-Activated Protein Kinase Kinase Kinase 12 (MAP3K12))

Bindungsspezifität: AA 828-859, C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAP3K12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This ZPK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 828-859 amino acids from the C-terminal region of human ZPK.

Klon: RB0976

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:2000. IHC-P: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-MAP3K12 Antikörper (ABIN391319)

Ye, Li, Yang, Xie, Yu, Ma, Zhu, Zhao, Lv: "MicroRNA-130a Targets MAP3K12 to Modulate Diabetic Endothelial Progenitor Cell Function." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 36, Issue 2, pp. 712-26, (2015) (PubMed).

Couture, Blouin: "The DLK gene is a transcriptional target of PPAR?." in: The Biochemical journal, Vol. 438, Issue 1, pp. 93-101, (2011) (PubMed).

Details zu MAP3K12

Target: MAP3K12 (Mitogen-Activated Protein Kinase Kinase Kinase 12 (MAP3K12))

Andere Bezeichnung: ZPK (MAP3K12 Produkte)

Synonyme: DLK antikoerper, MEKK12 antikoerper, MUK antikoerper, ZPK antikoerper, ZPKP1 antikoerper, PK antikoerper, Zpk antikoerper, zgc:77370 antikoerper, MGC151798 antikoerper, dlk antikoerper, map3k12 antikoerper, map3k12a antikoerper, mekk12 antikoerper, muk antikoerper, zpk antikoerper, zpkp1 antikoerper, DKFZp459K2433 antikoerper, map3k12-a antikoerper, map3k12-b antikoerper, map3k12b antikoerper, mitogen-activated protein kinase kinase kinase 12 antikoerper, mitogen activated protein kinase kinase kinase 12 antikoerper, mitogen-activated protein kinase kinase kinase 12 S homeolog antikoerper, mitogen-activated protein kinase kinase kinase 12 L homeolog antikoerper, MAP3K12 antikoerper, Map3k12 antikoerper, map3k12 antikoerper, map3k12.S antikoerper, map3k12.L antikoerper

Hintergrund: ZPK is a member of serine/threonine protein kinase family. This kinase contains a leucine-zipper domain, and is predominately expressed in neuronal cells. The phosphorylation state of this kinase in synaptic terminals was shown to be regulated by membrane depolarization via calcineurin. This kinase forms heterodimers with leucine zipper containing transcription factors, such as cAMP responsive element binding protein (CREB) and MYC, and thus may play a regulatory role in PKA or retinoic acid induced neuronal differentiation.

Molekulargewicht: 93219

Gen-ID: 7786

NCBI Accession: NP_001180440, NP_006292

UniProt: Q12852

Pathways: MAPK Signalweg