DAP Kinase 1 Antikörper (C-Term)

Produktnummer ABIN391321

Produktdetails anti-DAP Kinase 1 Antikörper

Target: DAP Kinase 1 (DAPK1) (Death-Associated Protein Kinase 1 (DAPK1))

Bindungsspezifität: AA 1360-1389, C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DAP Kinase 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This DAPK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1360-1389 amino acids from the C-terminal region of human DAPK1.

Klon: RB3033

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: IF: 1:10~50. WB: 1:1000. IHC-P: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-DAP Kinase 1 Antikörper (ABIN391321)

Bai, Zhang, Hu, Liu, Wang, Li, Lin, Zhang, Sun, Du, Song: "Silencing DNA methyltransferase 1 (DNMT1) inhibits proliferation, metastasis and invasion in ESCC by suppressing methylation of RASSF1A and DAPK." in: Oncotarget, Vol. 7, Issue 28, pp. 44129-44141, (2018) (PubMed).

Details zu DAP Kinase 1

Target: DAP Kinase 1 (DAPK1) (Death-Associated Protein Kinase 1 (DAPK1))

Andere Bezeichnung: DAP Kinase 1 (DAPK1) (DAPK1 Produkte)

Synonyme: DAPK1 antikoerper, MGC81366 antikoerper, si:ch211-66i11.1 antikoerper, wu:fj09c03 antikoerper, dapk antikoerper, MGC83745 antikoerper, 2310039H24Rik antikoerper, 2810425C21Rik antikoerper, AI642003 antikoerper, D13Ucla1 antikoerper, DAP-Kinase antikoerper, DAPK antikoerper, death-associated protein kinase 1 antikoerper, death associated protein kinase 1 L homeolog antikoerper, death associated protein kinase 1 antikoerper, death associated protein kinase 1 S homeolog antikoerper, LOC427465 antikoerper, dapk1.L antikoerper, DAPK1 antikoerper, dapk1 antikoerper, dapk1.S antikoerper, Dapk1 antikoerper

Hintergrund: Death-associated protein kinase 1 is a positive mediator of gamma-interferon induced programmed cell death (apoptosis). DAPK1 encodes a structurally unique 160-kD calmodulin dependent serine-threonine kinase that carries 8 ankyrin repeats and 2 putative P-loop consensus sites. It is a tumor suppressor candidate.

Molekulargewicht: 160046

Gen-ID: 1612

NCBI Accession: NP_004929

UniProt: P53355

Pathways: MAPK Signalweg, Interferon-gamma Pathway