MAPK10 Antikörper (N-Term)

Produktnummer ABIN391327

Produktdetails anti-MAPK10 Antikörper

Target: MAPK10 (Mitogen-Activated Protein Kinase 10 (MAPK10))

Bindungsspezifität: AA 7-34, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAPK10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MAPK10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7-34 amino acids from the N-terminal region of human MAPK10.

Klon: RB03190

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:25

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu MAPK10

Target: MAPK10 (Mitogen-Activated Protein Kinase 10 (MAPK10))

Andere Bezeichnung: MAPK10 (MAPK10 Produkte)

Synonyme: MAPK10 antikoerper, zgc:123234 antikoerper, DKFZp459H0638 antikoerper, Jnk3 antikoerper, SAPKC antikoerper, SAPb antikoerper, Serk2 antikoerper, JNK3 antikoerper, JNK3A antikoerper, PRKM10 antikoerper, SAPK1b antikoerper, p493F12 antikoerper, p54bSAPK antikoerper, C230008H04Rik antikoerper, JNK3B1 antikoerper, JNK3B2 antikoerper, SAPK(beta) antikoerper, ATMPK10 antikoerper, MAP kinase 10 antikoerper, mitogen-activated protein kinase 8 S homeolog antikoerper, mitogen-activated protein kinase 10 antikoerper, mitogen activated protein kinase 10 antikoerper, MAP kinase 10 antikoerper, mapk8.S antikoerper, MAPK10 antikoerper, mapk10 antikoerper, Mapk10 antikoerper, MPK10 antikoerper

Hintergrund: MAPK10 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This protein is a neuronal-specific form of c-Jun N-terminal kinases (JNKs). Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways during neuronal apoptosis. Beta-arrestin 2, a receptor-regulated MAP kinase scaffold protein, is found to interact with, and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (MKK4). Cyclin-dependent kinase 5 can phosphorylate, and inhibit the activity of this kinase, which may be important in preventing neuronal apoptosis.

Molekulargewicht: 52585

Gen-ID: 5602

NCBI Accession: NP_002744, NP_620446, NP_620447, NP_620448

UniProt: P53779

Pathways: MAPK Signalweg, WNT Signalweg, TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades