GOPC Antikörper (C-Term)

Produktnummer ABIN391394

Produktdetails anti-GOPC Antikörper

Target: GOPC (Golgi-Associated PDZ and Coiled-Coil Motif Containing (GOPC))

Bindungsspezifität: AA 361-390, C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GOPC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This PIST antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 361-390 amino acids from the C-terminal region of human PIST.

Klon: RB13073

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-GOPC Antikörper (ABIN391394)

Hnasko, Lin, McGarvey, Stanker: "A rapid method to improve protein detection by indirect ELISA." in: Biochemical and biophysical research communications, Vol. 410, Issue 4, pp. 726-31, (2011) (PubMed).

Details zu GOPC

Target: GOPC (Golgi-Associated PDZ and Coiled-Coil Motif Containing (GOPC))

Andere Bezeichnung: PIST (GOPC Produkte)

Synonyme: DKFZp459H2130 antikoerper, 2210402P09Rik antikoerper, AI844555 antikoerper, CAL antikoerper, FIG antikoerper, GOPC1 antikoerper, PIST antikoerper, fe38f01 antikoerper, wu:fe38f01 antikoerper, zgc:56254 antikoerper, zgc:65853 antikoerper, dJ94G16.2 antikoerper, cal antikoerper, gopc1 antikoerper, pist antikoerper, golgi associated PDZ and coiled-coil motif containing antikoerper, golgi-associated PDZ and coiled-coil motif containing antikoerper, golgi-associated PDZ and coiled-coil motif containing S homeolog antikoerper, GOPC antikoerper, Gopc antikoerper, gopc antikoerper, gopc.S antikoerper

Hintergrund: PDZ domains contain approximately 90 amino acids and bind the extreme C terminus of proteins in a sequence-specific manner. PIST, a PDZ domain-containing Golgi protein, was discovered in a yeast two-hybrid system as a binding partner to Beclin-1, a Bcl-2-interacting protein homologous to the yeast autophagy gene apg6. Experiments with mutant PIST proteins lacking the PDZ domain showed that PIST interaction with Beclin-1 through its coiled-coil domain can modulate Beclin-1 activity and suggest that PIST interactions with other proteins through its PDZ domain may regulate the activity of PIST and Beclin-1.

Molekulargewicht: 50520

Gen-ID: 57120

NCBI Accession: NP_001017408, NP_065132

UniProt: Q9HD26

Pathways: Maintenance of Protein Location, Asymmetric Protein Localization