Prohibitin 2 Antikörper (AA 225-255)
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- Target Alle Prohibitin 2 (PHB2) Antikörper anzeigen
- Prohibitin 2 (PHB2)
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Bindungsspezifität
- AA 225-255
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Prohibitin 2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Homologie
- B, Rat
- Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This PHB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 225-255 amino acids from human PHB2.
- Klon
- RB15576
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product PHB2 Primärantikörper
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- Applikationshinweise
- WB: 1:1000. IHC-P-Leica: 1:500. IHC-P-Leica: 1:250. IHC-P-Leica: 1:250
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Haltbarkeit
- 6 months
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- Target
- Prohibitin 2 (PHB2)
- Andere Bezeichnung
- PHB2 (PHB2 Produkte)
- Hintergrund
- PHB2 acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases. It functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. It competes with NCOA1 for modulation of ER transcriptional activity and is probably involved in regulating mitochondrial respiration activity and in aging.
- Molekulargewicht
- 33296
- Gen-ID
- 11331
- NCBI Accession
- NP_001138303, NP_001254629
- UniProt
- Q99623
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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