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MME Antikörper (C-Term)

Name: MME Antikörper (C-Term)
SKU: ABIN391499
Price: 467.5 EUR
Availability: InStock

MME Reaktivität: Human FACS, WB, IHC (p) Wirt: Kaninchen Polyclonal RB18821 unconjugated

Western blot analysis of Neprilysin Antibody (C-term) (ABIN391499 and ABIN2841464) in ,,Ramos cell line lysates (35 μg/lane). (MME Antikörper (C-Term))

Neprilysin Antibody (C-term) (ABIN391499 and ABIN2841464) flow cytometry analysis of Ramos cells (bottom histogram) compared to a negative control cell (top histogram). (MME Antikörper (C-Term))

FACS

Formalin-fixed and paraffin-embedded human kidney carcinoma with Neprilysin Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (MME Antikörper (C-Term))

IHC (p)

3 Abbildungen

Produktnummer ABIN391499

Datenblatt (PDF)

Target Alle MME Antikörper anzeigen

MME (Membrane Metallo-Endopeptidase (MME))
Bindungsspezifität
9

9

8

7

7

6

5

4

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1
AA 506-534, C-Term
Reaktivität
186

45

38

3

2

2

2

2

2

1

1

1

1
Human
Wirt
103

88

2
Kaninchen
Passende Sekundärantikörper
Klonalität
111

81

2
Polyklonal
Konjugat
107

18

16

11

7

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser MME Antikörper ist unkonjugiert
Applikation
102

76

74

60

39

27

20

17

10

8

5

5

3

2

2

2

1

1

1

1

1

1

1
Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie

M, Rb, Rat

Aufreinigung

This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen

This Neprilysin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 506-534 amino acids from the C-terminal region of human Neprilysin.

Klon

RB18821

Isotyp

Ig Fraction

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Applikationshinweise

WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit

6 months
Target

MME (Membrane Metallo-Endopeptidase (MME))

Andere Bezeichnung

Neprilysin (MME Produkte)

Substanzklasse

Chemical

Hintergrund

MME is a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85 % of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a oprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin.

Molekulargewicht

85514

Gen-ID

4311

NCBI Accession

NP_000893, NP_009218, NP_009219, NP_009220

UniProt

P08473

Pathways

RTK Signalweg, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration