This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This SAP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 285-314 amino acids from the Central region of human SAP.
PTX2 antikoerper, SAP antikoerper, Sap antikoerper, APCS antikoerper, FP antikoerper, SAP(FP) antikoerper, apcs antikoerper, ptx2 antikoerper, sap antikoerper, amyloid P component, serum antikoerper, serum amyloid P-component antikoerper, amyloid P component, serum protein L homeolog antikoerper, APCS antikoerper, Apcs antikoerper, apcs.L antikoerper
Hintergrund
PSAP is a highly conserved glycoprotein which is a precursor for 4 cleavage products: saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities.