VRK1 Antikörper (AA 366-396)

Produktnummer ABIN391605

Produktdetails anti-VRK1 Antikörper

Target: VRK1 (Vaccinia Related Kinase 1 (VRK1))

Bindungsspezifität: AA 366-396

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VRK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This VRK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 366-396 amino acids from the Central region of human VRK1.

Klon: RB2997

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu VRK1

Target: VRK1 (Vaccinia Related Kinase 1 (VRK1))

Andere Bezeichnung: VRK1 (VRK1 Produkte)

Synonyme: vrk1 antikoerper, MGC64390 antikoerper, MGC75762 antikoerper, VRK1 antikoerper, PCH1 antikoerper, PCH1A antikoerper, 51PK antikoerper, wu:fe16f06 antikoerper, zgc:56266 antikoerper, vaccinia related kinase 1 L homeolog antikoerper, vaccinia related kinase 1 antikoerper, Serine/threonine-protein kinase VRK1 antikoerper, vrk1.L antikoerper, vrk1 antikoerper, VRK1 antikoerper, vrk-1 antikoerper, Vrk1 antikoerper

Hintergrund: This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 Molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. This gene, therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN.

Molekulargewicht: 45476

Gen-ID: 7443

NCBI Accession: NP_003375

UniProt: Q99986