IDH1 Antikörper (AA 116-143)

Produktnummer ABIN391660

Produktdetails anti-IDH1 Antikörper

Target: IDH1 (Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1))

Bindungsspezifität: AA 116-143

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IDH1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: B, Rat, Sh

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This IDH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 116-143 amino acids from the Central region of human IDH1.

Klon: RB18238

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: IF: 1:10~50. WB: 1:1000. WB: 1:1000. IHC-P: 1:100. IHC-P: 1:50~100. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu IDH1

Target: IDH1 (Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1))

Andere Bezeichnung: IDH1 (IDH1 Produkte)

Synonyme: IDCD antikoerper, IDH antikoerper, IDP antikoerper, IDPC antikoerper, PICD antikoerper, NADP-CICDH antikoerper, AI314845 antikoerper, AI788952 antikoerper, E030024J03Rik antikoerper, Id-1 antikoerper, Idh-1 antikoerper, Idpc antikoerper, cb876 antikoerper, fm90e09 antikoerper, im:7143416 antikoerper, wu:fm90e09 antikoerper, F23E12.180 antikoerper, F23E12_180 antikoerper, IDH-I antikoerper, NAD+ DEPENDENT ISOCITRATE DEHYDROGENASE SUBUNIT 1 antikoerper, isocitrate dehydrogenase 1 antikoerper, isocitrate dehydrogenase I antikoerper, isocitrate dehydrogenase (NADP(+)) 1, cytosolic antikoerper, isocitrate dehydrogenase 1 (NADP+), soluble antikoerper, isocitrate dehydrogenase 1 (NADP+) L homeolog antikoerper, isocitrate dehydrogenase 1 antikoerper, IDH1 antikoerper, Idh1 antikoerper, idh1.L antikoerper, idh1 antikoerper

Hintergrund: IDH1 belongs to two distinct subclasses. The protein is the NADP(+)-dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes. This protein contains the PTS-1 peroxisomal targeting signal sequence. The presence of this enzyme in peroxisomes suggests roles in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanic acid. The cytoplasmic enzyme serves a significant role in cytoplasmic NADPH production.

Molekulargewicht: 46659

Gen-ID: 3417

NCBI Accession: NP_001269315, NP_001269316, NP_005887

UniProt: O75874

Pathways: Warburg Effekt