MAK Antikörper (C-Term)

Produktnummer ABIN391782

Produktdetails anti-MAK Antikörper

Target: MAK (Male Germ Cell-Associated Kinase (MAK))

Bindungsspezifität: AA 578-608, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MAK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 578-608 amino acids from the C-terminal region of human MAK.

Klon: RB3342

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-MAK Antikörper (ABIN391782)

Li, Rao, Zheng-Le, Hurd, Lillo, Khanna: "Loss of retinitis pigmentosa 2 (RP2) protein affects cone photoreceptor sensory cilium elongation in mice." in: Cytoskeleton (Hoboken, N.J.), (2015) (PubMed).

Tucker, Scheetz, Mullins, DeLuca, Hoffmann, Johnston, Jacobson, Sheffield, Stone: "Exome sequencing and analysis of induced pluripotent stem cells identify the cilia-related gene male germ cell-associated kinase (MAK) as a cause of retinitis pigmentosa." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 34, pp. E569-76, (2011) (PubMed).

Details zu MAK

Target: MAK (Male Germ Cell-Associated Kinase (MAK))

Andere Bezeichnung: MAK (MAK Produkte)

Synonyme: RP62 antikoerper, dJ417M14.2 antikoerper, A930010O05Rik antikoerper, Ick antikoerper, fj04c02 antikoerper, wu:fj04c02 antikoerper, zgc:56603 antikoerper, rp62 antikoerper, xmak antikoerper, MGC82717 antikoerper, MGC146434 antikoerper, male germ cell associated kinase antikoerper, male germ cell-associated kinase antikoerper, male germ cell associated kinase L homeolog antikoerper, MAK antikoerper, Mak antikoerper, mak antikoerper, mak.L antikoerper

Hintergrund: MAK is a serine/threonine protein kinase related to kinases involved in cell cycle regulation. It is expressed almost exclusively in the testis, primarily in germ cells. Studies of the mouse and rat homologs have localized the kinase to the chromosomes during meiosis in spermatogenesis, specifically to the synaptonemal complex that exists while homologous chromosomes are paired. There is, however, a study of the mouse homolog that has identified high levels of expression in developing sensory epithelia so its function may be more generalized.

Molekulargewicht: 70581

Gen-ID: 4117

NCBI Accession: NP_001229314, NP_001229886, NP_005897

UniProt: P20794