DYRK1A Antikörper (N-Term)

Produktnummer ABIN391798

Produktdetails anti-DYRK1A Antikörper

Target: DYRK1A (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A))

Bindungsspezifität: AA 107-136, N-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DYRK1A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: Rat, X

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This DYRK1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 107-136 amino acids from the N-terminal region of human DYRK1A.

Klon: RB13055

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000. IHC-P: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu DYRK1A

Target: DYRK1A (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A))

Andere Bezeichnung: DYRK1A (DYRK1A Produkte)

Synonyme: DYRK1A antikoerper, dyrk antikoerper, dyrk1 antikoerper, hp86 antikoerper, mnb antikoerper, mnbh antikoerper, DYRK antikoerper, DYRK1 antikoerper, HP86 antikoerper, MNB antikoerper, MNBH antikoerper, MRD7 antikoerper, 2310043O08Rik antikoerper, D16Ertd272e antikoerper, D16Ertd493e antikoerper, Dyrk antikoerper, ENSMUSG00000074897 antikoerper, Gm10783 antikoerper, Mnbh antikoerper, Mp86 antikoerper, mmb antikoerper, PSK47 antikoerper, dual specificity tyrosine phosphorylation regulated kinase 1A antikoerper, dual specificity tyrosine-(Y)-phosphorylation regulated kinase 1A antikoerper, dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a antikoerper, dual specificity tyrosine-(Y)-phosphorylation regulated kinase 1A S homeolog antikoerper, DYRK1A antikoerper, dyrk1a antikoerper, Dyrk1a antikoerper, dyrk1a.S antikoerper

Hintergrund: DYRK1A is a member of the Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family. This member contains a nuclear targeting signal sequence, a protein kinase domain, a leucine zipper motif, and a highly conservative 13-consecutive-histidine repeat. It catalyzes its autophosphorylation on serine/threonine and tyrosine residues. It may play a significant role in a signaling pathway regulating cell proliferation and may be involved in brain development. The DYRK1A gene is a homolog of Drosophila mnb (minibrain) gene and rat Dyrk gene. It is localized in the Down syndrome critical region of chromosome 21, and is considered to be a strong candidate gene for learning defects associated with Down syndrome.

Molekulargewicht: 85584

Gen-ID: 1859

NCBI Accession: NP_001387, NP_567824, NP_569120, NP_569122

UniProt: Q13627

Pathways: Mitotic G1-G1/S Phases