ACO2 Antikörper (AA 294-325)
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- Target Alle ACO2 Antikörper anzeigen
- ACO2 (Aconitase 2, Mitochondrial (ACO2))
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Bindungsspezifität
- AA 294-325
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ACO2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Aufreinigung
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Immunogen
- This ACO2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 294-325 amino acids from the Central region of human ACO2.
- Klon
- RB14646
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product ACO2 Primärantikörper
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- Applikationshinweise
- WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Haltbarkeit
- 6 months
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Malarial infection develops mitochondrial pathology and mitochondrial oxidative stress to promote hepatocyte apoptosis." in: Free radical biology & medicine, Vol. 46, Issue 2, pp. 271-81, (2009) (PubMed).
: "
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Malarial infection develops mitochondrial pathology and mitochondrial oxidative stress to promote hepatocyte apoptosis." in: Free radical biology & medicine, Vol. 46, Issue 2, pp. 271-81, (2009) (PubMed).
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- Target
- ACO2 (Aconitase 2, Mitochondrial (ACO2))
- Andere Bezeichnung
- ACO2 (ACO2 Produkte)
- Hintergrund
- ACO2 belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification.
- Molekulargewicht
- 85425
- Gen-ID
- 50
- NCBI Accession
- NP_001089
- UniProt
- Q99798
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