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Caspase 3 Antikörper (AA 60-90)

CASP3 Reaktivität: Human WB, IHC (p), FACS Wirt: Kaninchen Polyclonal RB14696 unconjugated
Produktnummer ABIN391813
  • Target Alle Caspase 3 (CASP3) Antikörper anzeigen
    Caspase 3 (CASP3)
    Bindungsspezifität
    • 19
    • 16
    • 16
    • 16
    • 16
    • 16
    • 15
    • 15
    • 13
    • 12
    • 12
    • 10
    • 9
    • 8
    • 8
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 60-90
    Reaktivität
    • 257
    • 175
    • 129
    • 17
    • 11
    • 10
    • 9
    • 8
    • 7
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 259
    • 38
    • 4
    • 2
    • 2
    Kaninchen
    Klonalität
    • 255
    • 49
    Polyklonal
    Konjugat
    • 152
    • 24
    • 20
    • 13
    • 10
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Dieser Caspase 3 Antikörper ist unkonjugiert
    Applikation
    • 229
    • 108
    • 100
    • 83
    • 67
    • 65
    • 47
    • 34
    • 30
    • 29
    • 26
    • 20
    • 10
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This Caspase-3 (CASP3) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 60-90 amino acids from the Central region of human Caspase-3 (CASP3).
    Klon
    RB14696
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product CASP3 Primärantikörper
  • Applikationshinweise
    WB: 1:2000. WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Zhao, Xia, Zhang, Xiong, Li, Yan, Chen, Wang, Wang, Gao, Lee, Li, Wang, Zhang, Tao: "Nucleostemin dysregulation contributes to ischemic vulnerability of diabetic hearts: Role of ribosomal biogenesis." in: Journal of molecular and cellular cardiology, Vol. 108, pp. 106-113, (2018) (PubMed).

    Ling, Song, Fan, Feng, Liu, Yang, Wang, Li, Tian, Zhao, Liu, Huang, Hou, Xu, Shi, Li: "Combination of metformin and sorafenib suppresses proliferation and induces autophagy of hepatocellular carcinoma via targeting the mTOR pathway." in: International journal of oncology, Vol. 50, Issue 1, pp. 297-309, (2017) (PubMed).

    Guo, Shao, Chen, Xu, Zhang, Liu: "Expression of pituitary tumor-transforming 2 in human glioblastoma cell lines and its role in glioblastoma tumorigenesis." in: Experimental and therapeutic medicine, Vol. 11, Issue 5, pp. 1847-1852, (2016) (PubMed).

    Liu, Xie, Wang, Liu, Liu, Sun, Niu: "Ubenimex inhibits cell proliferation, migration and invasion in renal cell carcinoma: the effect is autophagy-associated." in: Oncology reports, Vol. 33, Issue 3, pp. 1372-80, (2015) (PubMed).

    Tai, Sun, Liu, Ding, Hsia, Bhuta, Thor, Damoiseaux, Liang, Huang: "Combination of Rad001 (everolimus) and propachlor synergistically induces apoptosis through enhanced autophagy in prostate cancer cells." in: Molecular cancer therapeutics, Vol. 11, Issue 6, pp. 1320-31, (2012) (PubMed).

  • Target
    Caspase 3 (CASP3)
    Andere Bezeichnung
    Caspase-3 (CASP3) (CASP3 Produkte)
    Synonyme
    CPP32 antikoerper, CPP32B antikoerper, SCA-1 antikoerper, A830040C14Rik antikoerper, AC-3 antikoerper, Apopain antikoerper, CC3 antikoerper, Caspase-3 antikoerper, Lice antikoerper, Yama antikoerper, mldy antikoerper, xcpp32 antikoerper, casp3 antikoerper, zgc:100890 antikoerper, CASP-3 antikoerper, caspase-3 antikoerper, caspase 3 antikoerper, caspase 3 S homeolog antikoerper, caspase 3, apoptosis-related cysteine peptidase a antikoerper, caspase 3, apoptosis-related cysteine peptidase antikoerper, CASP3 antikoerper, Casp3 antikoerper, casp3.S antikoerper, casp3a antikoerper
    Hintergrund
    CASP3 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease.
    Molekulargewicht
    31608
    Gen-ID
    836
    NCBI Accession
    NP_004337, NP_116786
    UniProt
    P42574
    Pathways
    Apoptose, Caspase Kaskade in der Apoptose, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation
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