EPH Receptor A5 Antikörper (C-Term)

Produktnummer ABIN391893

Produktdetails anti-EPH Receptor A5 Antikörper

Target: EPH Receptor A5 (EPHA5)

Bindungsspezifität: AA 942-972, C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EPH Receptor A5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This EphA5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 942-972 amino acids from the C-terminal region of human EphA5.

Klon: RB1658

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-EPH Receptor A5 Antikörper (ABIN391893)

Wang, Xu, Wu, Chen, Wang: "Decreased expression of EphA5 is associated with Fuhrman nuclear grade and pathological tumour stage in ccRCC." in: International journal of experimental pathology, Vol. 98, Issue 1, pp. 34-39, (2017) (PubMed).

Details zu EPH Receptor A5

Target: EPH Receptor A5 (EPHA5)

Andere Bezeichnung: EphA5 (EPHA5 Produkte)

Synonyme: CEK7 antikoerper, EHK-1 antikoerper, EHK1 antikoerper, EK7 antikoerper, HEK7 antikoerper, TYRO4 antikoerper, AI854630 antikoerper, AW125296 antikoerper, Cek7 antikoerper, Ehk1 antikoerper, Els1 antikoerper, Hek7 antikoerper, Rek7 antikoerper, bsk antikoerper, Els1. antikoerper, EPHA5 antikoerper, EPH receptor A5 antikoerper, Eph receptor A5 antikoerper, EPHA5 antikoerper, epha5 antikoerper, Epha5 antikoerper

Hintergrund: Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).

Molekulargewicht: 114803

Gen-ID: 2044

NCBI Accession: NP_004430, NP_872272

UniProt: P54756

Pathways: RTK Signalweg