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EPH Receptor B1 Antikörper (C-Term)

EPHB1 Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB1648 unconjugated
Produktnummer ABIN391917
  • Target Alle EPH Receptor B1 (EPHB1) Antikörper anzeigen
    EPH Receptor B1 (EPHB1)
    Bindungsspezifität
    • 22
    • 15
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 955-984, C-Term
    Reaktivität
    • 57
    • 48
    • 40
    • 1
    Human, Maus
    Wirt
    • 64
    • 4
    • 4
    Kaninchen
    Klonalität
    • 70
    • 2
    Polyklonal
    Konjugat
    • 31
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser EPH Receptor B1 Antikörper ist unkonjugiert
    Applikation
    • 62
    • 27
    • 27
    • 27
    • 13
    • 11
    • 7
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This EphB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 955-984 amino acids from the C-terminal region of human EphB1.
    Klon
    RB1648
    Isotyp
    Ig Fraction
  • Applikationshinweise
    WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. IHC-P: 1:50~100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Sheng, Wang, Dong, Ma, Zhou, Sugimura, Lu, Zhou: "EphB1 is underexpressed in poorly differentiated colorectal cancers." in: Pathobiology : journal of immunopathology, molecular and cellular biology, Vol. 75, Issue 5, pp. 274-80, (2008) (PubMed).

    Wang, Dong, Sheng, Ma, Li, Wang, Lu, Sugimura, Jin, Zhou: "Loss of expression of EphB1 protein in gastric carcinoma associated with invasion and metastasis." in: Oncology, Vol. 73, Issue 3-4, pp. 238-45, (2008) (PubMed).

  • Target
    EPH Receptor B1 (EPHB1)
    Andere Bezeichnung
    EphB1 (EPHB1 Produkte)
    Synonyme
    ELK antikoerper, EPHT2 antikoerper, Hek6 antikoerper, NET antikoerper, ephb1-a antikoerper, xek antikoerper, Xek antikoerper, MGC89790 antikoerper, EPHB1 antikoerper, CEK6 antikoerper, EK6 antikoerper, 9330129L11 antikoerper, AW488255 antikoerper, C130099E04Rik antikoerper, Cek6 antikoerper, ENSMUSG00000074119 antikoerper, Elk antikoerper, Elkh antikoerper, Net antikoerper, Ephb2 antikoerper, Erk antikoerper, elk antikoerper, EPH receptor B1 antikoerper, EPH receptor B1 S homeolog antikoerper, ephrin type-B receptor 1 antikoerper, Eph receptor B1 antikoerper, EPHB1 antikoerper, ephb1.S antikoerper, ephb1 antikoerper, LOC100467687 antikoerper, Ephb1 antikoerper
    Hintergrund
    Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).
    Molekulargewicht
    109885
    Gen-ID
    2047
    NCBI Accession
    NP_004432
    UniProt
    P54762
    Pathways
    RTK Signalweg
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