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FGFR2 Antikörper
FGFR2
Reaktivität: Human
WB, FACS, IF, IHC (p)
Wirt: Kaninchen
Polyclonal
RB17696
unconjugated
Produktdetails anti-FGFR2 Antikörper
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Target
Alle FGFR2 Antikörper anzeigen
FGFR2
(Fibroblast Growth Factor Receptor 2 (FGFR2))
Reaktivität
Alle Reaktivitäten für FGFR2 Antikörper
Human
Wirt
Alle Wirte für FGFR2 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für FGFR2 Antikörper
Polyklonal
Konjugat
Alle Konjugate für FGFR2 Antikörper
Dieser FGFR2 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für FGFR2 Antikörper
Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Aufreinigung
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This FGFR2 antibody is generated from rabbits immunized with a his tag recombinant protein of human FGFR2.
Klon
RB17696
Isotyp
Ig Fraction
Top Product
Discover our top product FGFR2 Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
IF: 1:10~50. WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Haltbarkeit
6 months
Details zu FGFR2
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Target
FGFR2
(Fibroblast Growth Factor Receptor 2 (FGFR2))
Andere Bezeichnung
FGFR2 (FGFR2 Produkte )
Synonyme
FGFR2 antikoerper, FGFR2IIIb antikoerper, bek antikoerper, bfr-1 antikoerper, cd332 antikoerper, cek3 antikoerper, cfd1 antikoerper, ect1 antikoerper, fgfr-2 antikoerper, jws antikoerper, k-sam antikoerper, kgfr antikoerper, tk14 antikoerper, tk25 antikoerper, xfgfr2 antikoerper, DKFZp469H1521 antikoerper, BBDS antikoerper, BEK antikoerper, BFR-1 antikoerper, CD332 antikoerper, CEK3 antikoerper, CFD1 antikoerper, ECT1 antikoerper, JWS antikoerper, K-SAM antikoerper, KGFR antikoerper, TK14 antikoerper, TK25 antikoerper, AU043015 antikoerper, AW556123 antikoerper, Bek antikoerper, Fgfr-2 antikoerper, Fgfr-7 antikoerper, Fgfr7 antikoerper, KGFRTr antikoerper, svs antikoerper, FGF-R antikoerper, fgfr72IIIb antikoerper, FGFR antikoerper, fc56c05 antikoerper, wu:fc56c05 antikoerper, fibroblast growth factor receptor 2 antikoerper, fibroblast growth factor receptor 2 L homeolog antikoerper, FGFR2 antikoerper, LOC100084641 antikoerper, fgfr2 antikoerper, Fgfr2 antikoerper, fgfr2.L antikoerper
Hintergrund
FGFR2 is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. Mutations in FGFR2 gene are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrata syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis.
Molekulargewicht
92025
Gen-ID
2263
NCBI Accession
NP_000132 , NP_001138385 , NP_001138386 , NP_001138387 , NP_001138388 , NP_001138389 , NP_001138390 , NP_001138391 , NP_075259 , NP_075418
UniProt
P21802
Pathways
RTK Signalweg , Fc-epsilon Rezeptor Signalübertragung , EGFR Signaling Pathway , Neurotrophin Signalübertragung , Regulation of Muscle Cell Differentiation , Skeletal Muscle Fiber Development , Growth Factor Binding
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