LTK Antikörper (N-Term)

Produktnummer ABIN392012

Produktdetails anti-LTK Antikörper

Target: LTK (Leukocyte Receptor tyrosine Kinase (LTK))

Bindungsspezifität: AA 42-72, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LTK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This LTK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 42-72 amino acids from the N-terminal region of human LTK.

Klon: RB1528

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu LTK

Target: LTK (Leukocyte Receptor tyrosine Kinase (LTK))

Andere Bezeichnung: LTK (LTK Produkte)

Synonyme: LTK antikoerper, ALK antikoerper, TYK1 antikoerper, si:dz107o16.1 antikoerper, leukocyte receptor tyrosine kinase antikoerper, leukocyte tyrosine kinase antikoerper, Ltk antikoerper, LTK antikoerper, ltk antikoerper

Hintergrund: Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).

Molekulargewicht: 91681

Gen-ID: 4058

NCBI Accession: NP_001129157, NP_002335, NP_996844

UniProt: P29376

Pathways: RTK Signalweg