×
Aktivieren Sie Javascript in Ihrem Browser, um unsere Webseite optimal zu nutzen.
DDR1 Antikörper
DDR1
Reaktivität: Human
WB, IHC (p)
Wirt: Kaninchen
Polyclonal
RB14725
unconjugated
Produktdetails anti-DDR1 Antikörper
(ausblenden)
Target
Alle DDR1 Antikörper anzeigen
DDR1
(Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))
Reaktivität
Alle Reaktivitäten für DDR1 Antikörper
Human
Wirt
Alle Wirte für DDR1 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für DDR1 Antikörper
Polyklonal
Konjugat
Alle Konjugate für DDR1 Antikörper
Dieser DDR1 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für DDR1 Antikörper
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Aufreinigung
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This MCK10 antibody is generated from rabbits immunized with recombinant human MCK10 protein.
Klon
RB14725
Isotyp
Ig Fraction
Top Product
Discover our top product DDR1 Primärantikörper
Alternativen
(anzeigen)
Anwendungsinformationen
(ausblenden)
Applikationshinweise
WB: 1:1000. IHC-P: 1:10~50
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
(ausblenden)
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Haltbarkeit
6 months
Details zu DDR1
(ausblenden)
Target
DDR1
(Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))
Andere Bezeichnung
MCK10 (DDR1 Produkte )
Synonyme
CG11573 antikoerper, CG13984 antikoerper, CG13985 antikoerper, CG33531 antikoerper, CG9488 antikoerper, CG9490 antikoerper, CT33540 antikoerper, DDR antikoerper, Dmel\\CG33531 antikoerper, Dmel_CG13984 antikoerper, 6030432F18 antikoerper, AI323681 antikoerper, CD167a antikoerper, Cak antikoerper, Nep antikoerper, PTK3A antikoerper, CAK antikoerper, CD167 antikoerper, EDDR1 antikoerper, HGK2 antikoerper, MCK10 antikoerper, NEP antikoerper, NTRK4 antikoerper, PTK3 antikoerper, RTK6 antikoerper, TRKE antikoerper, Drd1 antikoerper, PTK3D antikoerper, Discoidin domain receptor antikoerper, discoidin domain receptor family, member 1 antikoerper, discoidin domain receptor tyrosine kinase 1 antikoerper, Ddr antikoerper, Ddr1 antikoerper, DDR1 antikoerper
Hintergrund
Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation and metabolism. MCK10 is a RTK that is widely expressed in normal and transformed epithelial cells and is activated by various types of collagen. This protein belongs to a subfamily of tyrosine kinase receptors with a homology region to the Dictyostelium discoideum protein discoidin I in their extracellular domain. Its autophosphorylation is achieved by all collagens so far tested (type I to type VI). In situ studies and Northern-blot analysis showed that expression of this encoded protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, this protein is significantly over-expressed in several human tumors from breast, ovarian, esophageal, and pediatric brain.
Molekulargewicht
101128
Gen-ID
780
NCBI Accession
NP_001189450 , NP_001189451 , NP_001189452 , NP_001945 , NP_054699 , NP_054700
UniProt
Q08345
Pathways
RTK Signalweg , Smooth Muscle Cell Migration
Zuletzt angesehen
(ausblenden)