MUSK Antikörper

Produktnummer ABIN392021

Produktdetails anti-MUSK Antikörper

Target: MUSK (Muscle, Skeletal, Receptor Tyrosine Kinase (MUSK))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MUSK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This MUSK antibody is generated from rabbits immunized with human MUSK recombinant protein.

Klon: RB14743

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: IF: 1:10~50. WB: 1:1000. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu MUSK

Target: MUSK (Muscle, Skeletal, Receptor Tyrosine Kinase (MUSK))

Andere Bezeichnung: MUSK (MUSK Produkte)

Synonyme: unp antikoerper, fj98e12 antikoerper, zgc:63467 antikoerper, wu:fj98e12 antikoerper, si:dz46m7.2 antikoerper, si:dz57f23.3 antikoerper, si:busm1-57f23.3 antikoerper, musk-A antikoerper, MuSK antikoerper, MUSK antikoerper, Mdk4 antikoerper, Mlk antikoerper, Nsk1 antikoerper, Nsk2 antikoerper, Nsk3 antikoerper, muscle antikoerper, muscle associated receptor tyrosine kinase antikoerper, muscle, skeletal, receptor tyrosine kinase antikoerper, muscle associated receptor tyrosine kinase S homeolog antikoerper, MUSK antikoerper, musk antikoerper, musk.S antikoerper, Musk antikoerper

Hintergrund: MuSK activates signaling cascades responsible for many aspects of synapse formation, including the organization of the postsynaptic membrane, synapse-specific transcription, and presynaptic differentiation. MuSK also mediates agrin-induced aggregation of acetylcholine receptors at the mature vertebrate neuromuscular junction and also during synapse formation. It has been shown that a majority of AChR Ab-seronegative myasthenia gravis patients possess serum autoantibodies against MuSK.

Molekulargewicht: 97056

Gen-ID: 4593

NCBI Accession: NP_001159752, NP_001159753, NP_005583

UniProt: O15146

Pathways: RTK Signalweg, Regulation of Muscle Cell Differentiation, Synaptic Membrane, Regulation of Cell Size, Skeletal Muscle Fiber Development