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Ret Proto-Oncogene Antikörper (C-Term)

Name: Ret Proto-Oncogene Antikörper (C-Term)
SKU: ABIN392041
Price: 445.5 EUR
Availability: InStock

RET Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB01561 unconjugated

Western blot analysis of RET (arrow) using rabbit polyclonal RET Antibody (C-term ) (ABIN392041 and ABIN2841809). (Ret Proto-Oncogene Antikörper (C-Term))

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (Ret Proto-Oncogene Antikörper (C-Term))

IHC (p)

2 Abbildungen

(1 reference)

Produktnummer ABIN392041

Datenblatt (PDF)

Target Alle Ret Proto-Oncogene (RET) Antikörper anzeigen

Ret Proto-Oncogene (RET)
Bindungsspezifität
25

20

15

15

15

10

9

8

8

8

8

7

6

6

4

4

4

3

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 1012-1042, C-Term
Reaktivität
159

102

82

5

3

2

2

2

2

1

1

1

1

1

1
Human
Wirt
182

22

2

2

1

1
Kaninchen
Passende Sekundärantikörper
Klonalität
180

30
Polyklonal
Konjugat
87

14

10

9

6

5

5

5

5

5

5

5

5

5

5

5

4

4

4

4

4

4

4

1
Dieser Ret Proto-Oncogene Antikörper ist unkonjugiert
Applikation
169

83

66

65

40

28

17

16

14

9

4

3

2

1

1

1

1

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen

This RET antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1012-1042 amino acids from the C-terminal region of human RET.

Klon

RB01561

Isotyp

Ig Fraction

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RET Reaktivität: Human WB, PLA Wirt: Kaninchen Polyclonal unconjugated

anti-Ret Proto-Oncogene (RET) (AA 702-848) antibody
RET Reaktivität: Human ELISA, Coat Wirt: Maus Monoclonal RET-2663 unconjugated

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RET Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB00705 unconjugated

anti-Ret Proto-Oncogene (RET) (AA 361-458) antibody
RET Reaktivität: Human WB, ELISA, PLA Wirt: Maus Monoclonal 1A5 unconjugated

anti-Ret Proto-Oncogene (RET) (C-Term) antibody
RET Reaktivität: Human, Maus, Ratte WB, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Ret Proto-Oncogene (RET) (pTyr1062) antibody
RET Reaktivität: Human, Maus, Ratte WB, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Ret Proto-Oncogene (RET) (AA 29-300) antibody
RET Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

anti-Ret Proto-Oncogene (RET) (AA 541-553), (Extracellular), (N-Term) antibody
RET Reaktivität: Human, Maus, Ratte WB, IHC, IF, FACS, ICC, LCI Wirt: Kaninchen Polyclonal unconjugated

anti-Ret Proto-Oncogene (RET) (AA 29-300) antibody
RET Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

WB: 1:1000. IHC-P: 1:50~100

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit

6 months
de Martimprey, Bertrand, Fusco, Santoro, Couvreur, Vauthier, Malvy: "siRNA nanoformulation against the ret/PTC1 junction oncogene is efficient in an in vivo model of papillary thyroid carcinoma." in: Nucleic acids research, Vol. 36, Issue 1, pp. e2, (2008) (PubMed).
Target

Ret Proto-Oncogene (RET)

Andere Bezeichnung

RET (RET Produkte)

Synonyme

c-ret antikoerper, cret antikoerper, etID315074.13 antikoerper, ret1 antikoerper, wu:fd13h01 antikoerper, X-ret antikoerper, ret-A antikoerper, xret antikoerper, RET antikoerper, MTC1 antikoerper, CDHF12 antikoerper, CDHR16 antikoerper, HSCR1 antikoerper, MEN2A antikoerper, MEN2B antikoerper, PTC antikoerper, RET-ELE1 antikoerper, RET51 antikoerper, RET9 antikoerper, c-Ret antikoerper, ret proto-oncogene receptor tyrosine kinase antikoerper, ret proto-oncogene S homeolog antikoerper, ret proto-oncogene antikoerper, ret antikoerper, ret.S antikoerper, RET antikoerper, Ret antikoerper

Hintergrund

RET, a member of the cadherin superfamily, is one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This protein plays a crucial role in neural crest development, and the gene can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations i are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma.

Molekulargewicht

124319

Gen-ID

5979

NCBI Accession

NP_065681, NP_066124

UniProt

P07949

Pathways

RTK Signalweg, Dopaminergic Neurogenesis, Regulation of Cell Size, Tube Formation