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DOK4 Antikörper (C-Term)

DOK4 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB1779-1780 unconjugated
Produktnummer ABIN392073
  • Target Alle DOK4 Antikörper anzeigen
    DOK4 (Docking Protein 4 (DOK4))
    Bindungsspezifität
    • 15
    • 6
    • 6
    • 4
    • 4
    • 2
    • 1
    • 1
    AA 228-258, C-Term
    Reaktivität
    • 49
    • 17
    • 14
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 49
    Kaninchen
    Klonalität
    • 49
    Polyklonal
    Konjugat
    • 18
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DOK4 Antikörper ist unkonjugiert
    Applikation
    • 34
    • 17
    • 17
    • 13
    • 13
    • 8
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    M
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This DOK4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 228-258 amino acids from the C-terminal region of human DOK4.
    Klon
    RB1779-1780
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product DOK4 Primärantikörper
  • Applikationshinweise
    WB: 1:1000. IHC-P: 1:50~100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Tatarov, Mitchell, Seywright, Leung, Brunton, Edwards: "SRC family kinase activity is up-regulated in hormone-refractory prostate cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 15, Issue 10, pp. 3540-9, (2009) (PubMed).

  • Target
    DOK4 (Docking Protein 4 (DOK4))
    Andere Bezeichnung
    DOK4 (DOK4 Produkte)
    Synonyme
    DOK4 antikoerper, docking protein 4 antikoerper, DOK4 antikoerper, Dok4 antikoerper
    Hintergrund
    Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).
    Molekulargewicht
    37028
    Gen-ID
    55715
    NCBI Accession
    NP_060580
    UniProt
    Q8TEW6
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