RUNX2 Antikörper (AA 445-474)

Produktnummer ABIN392133

Produktdetails anti-RUNX2 Antikörper

Target: RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))

Bindungsspezifität: AA 445-474

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RUNX2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This RUNX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 445-474 amino acids surrounding S465 of human RUNX2.

Klon: RB15321

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:2000. IHC-P: 1:10~50. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu RUNX2

Target: RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))

Andere Bezeichnung: RUNX2 (RUNX2 Produkte)

Synonyme: AML3 antikoerper, CBF-alpha-1 antikoerper, CBFA1 antikoerper, CCD antikoerper, CCD1 antikoerper, CLCD antikoerper, OSF-2 antikoerper, OSF2 antikoerper, PEA2aA antikoerper, PEBP2aA antikoerper, Cbf antikoerper, Cbfa-1 antikoerper, Cbfa1 antikoerper, LS3 antikoerper, Osf2 antikoerper, Pebp2a1 antikoerper, Pebpa2a antikoerper, runx2 antikoerper, RUNX2 antikoerper, ccd antikoerper, aml3 antikoerper, ccd1 antikoerper, osf2 antikoerper, cbfa1 antikoerper, pea2aa antikoerper, pebp2a1 antikoerper, pebp2a2 antikoerper, pebp2aa antikoerper, pebp2aa1 antikoerper, runt related transcription factor 2 antikoerper, runt-related transcription factor 2a antikoerper, runt-related transcription factor 2 antikoerper, runt related transcription factor 2 L homeolog antikoerper, RUNX2 antikoerper, runx2a antikoerper, Runx2 antikoerper, runx2 antikoerper, LOC703331 antikoerper, LOC100549663 antikoerper, runx2.L antikoerper

Hintergrund: Runx2 is a member of the RUNX family of transcription factors. It is a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. It can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in the Runx2 gene have been associated with the bone development disorder cleidocranial dysplasia (CCD).

Molekulargewicht: 56648

Gen-ID: 860

NCBI Accession: NP_001015051, NP_001019801

UniProt: Q13950