PDX1 Antikörper (N-Term)

Produktnummer ABIN392140

Produktdetails anti-PDX1 Antikörper

Target: PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))

Bindungsspezifität: AA 40-69, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PDX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-69 amino acids from the N-terminal region of human PDX1.

Klon: RB10459

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu PDX1

Target: PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))

Andere Bezeichnung: PDX1 (PDX1 Produkte)

Synonyme: GSF antikoerper, IDX-1 antikoerper, IPF1 antikoerper, IUF1 antikoerper, MODY4 antikoerper, PDX-1 antikoerper, STF-1 antikoerper, ipf1 antikoerper, PDX1 antikoerper, IPF-1 antikoerper, Ipf1 antikoerper, Mody4 antikoerper, pdx-1 antikoerper, Idx1 antikoerper, Stf1 antikoerper, zgc:100874 antikoerper, XlHbox-8 antikoerper, xlhbox8 antikoerper, pancreatic and duodenal homeobox 1 antikoerper, pancreatic and duodenal homeobox 1 S homeolog antikoerper, PDX1 antikoerper, pdx1 antikoerper, Pdx1 antikoerper, pdx1.S antikoerper

Hintergrund: PDX1 is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. This nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in the gene encoding PDX1 are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).

Molekulargewicht: 30771

Gen-ID: 3651

NCBI Accession: NP_000200

UniProt: P52945

Pathways: Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Hormone Transport, Carbohydrate Homeostasis, Chromatin Binding, Maintenance of Protein Location